Banner for the CNS Metastasis Symposium

Watch Recordings

Bringing together leading clinicians and scientists, as well as trainees, this live and virtual half day event will provide a comprehensive overview of the latest in treatment and clinical, basic, and translational research throughout UCSF in the area of central nervous system metastatic disease. There is no cost for this program, but registration is required and CME credits are not available. 

Lunch will be served following the event, and we encourage participants to come with questions and ideas for future direction and collaborations. 

Registration link

In-person location: Fisher West Banquet Hall in the Mission Bay Conference Center (1675 Owens Street, San Francisco, CA 94158)


8:00-8:10 AM       Opening Remarks: John de Groot, MD


Introduction by: Mariza Daras, MD

8:15–8:30 AM             Adil Daud, MD

Clinical Professor of Medicine, Division of Hematology Oncology

Mechanisms of PD1 resistance in melanoma and the combinatorial approach to therapies: quadruple checkpoint blockade

8:30–8:45 AM             Mariza Daras, MD

Associate Professor, Division of Neuro-oncology

Overcoming the blood brain barrier in the management of CNS metastases

8:45–9:00 AM             Steve Braunstein, MD, PhD

Associate Professor, Department of Radiation Oncology

The role of brachytherapy in recurrent CNS metastases

9:00–9:15 AM             Manish Aghi, MD, PhD

Professor, Department of Neurological Surgery

Laser interstitial thermal therapy in management of RT necrosis and treatment refractory brain metastases

9:15–9:30 AM             Javier Villanueva-Meyer, MD

Assistant Professor, Department of Clinical Radiology

Advanced Imaging in the early detection of brain metastases and in differentiating progression from treatment-related inflammation

9:30–9:40 AM            Questions/Discussion



Introduction by: Michelle Melisko, MD

9:45–10:05 AM           Hugo Gonzalez Velozo, PhD

Postdoctoral Scholar, Department of Anatomy

Cell Archetypes in Human Brain Metastases: Connecting Tumor Cell Programs, and Tumor Microenvironment

10:05–10:25 AM         Laura Huppert, MD

Assistant Clinical Professor, Division of Hematology Oncology

Chris Im, PhD

Postdoctoral Scholar, Department of Pathology

CSF Immune profiling in leptomeningeal disease

10:25–10:45 AM         Harish Vasudevan, MD, PhD

Assistant Professor, Department of Radiation Oncology

Mutational analysis and single cell sequencing of melanoma brain metastases

10:45–11:05 AM         Joanna Phillips, MD, PhD

Professor, Departments of Neurological Surgery and Pathology

Co-director of the UCSF Brain Tumor SPORE Biorepository

CNS metastasis biobanking: a critical resource in translational efforts

11:05–11:15 AM         Questions/Discussion



Introduction by: Steve Braunstein, MD, PhD

11:20–11:30 AM          Oral Presentation 1 – Ramin Morshed, MD (Dept of Neurosurgery)

Supervised machine learning identifies risk factors associated with leptomeningeal disease after surgical resection of brain metastases

11:30–11:40 AM          Oral Presentation 2 – Lisa Ni, MD (Dept of Radiation Oncology)

Volumetric Response of Brain Metastases in EGFR mutant NSCLC treated with Osimertinib alone vs in combination with RT

11:40–11:50 AM          Oral Presentation 3 – William Chen, MD (Dept of Radiation Oncology)

Radiosurgery in eloquent areas: efficacy and safety of stereotactic radiosurgery for brainstem metastases


11:50 AM–12:00 PM       Closing Remarks: Mariza Daras, MD - The UCSF CNS Metastasis Experience: Future areas of growth and opportunity                                  


12:00 PM                        Lunch and Discussion on Future Efforts/Collaborations


Symposium Organizers

Mariza Daras, MD

Mariza Daras, MD

Course Co-Director


Michelle Melisko, MD

Michelle Melisko, MD

Course Co-Director


John de Groot, MD

John de Groot, MD

Senior Advisor