A three step process adds ubiquitin to proteins and targets them for proteasomal degradation

Medical questions
call 415/353-7500
fax 415/353-2889
Residency Program
call 415/353-3904
fax 415/353-3907
Principal Investigator
Professor of Neurological Surgery
Suzanne Marie and Robert Vincent Haderle Endowed Chair in Molecular Neuro-Oncology
Director of Basic Science, Brain Tumor Research Center
Jean Nakamura MD
Postdoctoral Fellow
Amith Panner PhD
Post-doctoral Fellow
Changjiang Weng PhD
Post-doctoral Fellow
Alberto Felletti MD
Visiting Fellow
Lingjie Guan PhD
Post-doctoral Fellow
UCSF Helen Diller Family Comprehensive Cancer Center
• RO1 CA100011 – Russell O. Pieper. P.I.
Award Period 12/01/03 to 11/30/08
Total Direct Costs $1,250,000
Funding Agency: National Cancer Institute
Title: p38, G2 arrest, and temozolomide resistance in gliomas.
• RO1 CA 115638 – Russell O. Pieper, P.I.
Award Period 4/1/06 to 3/31/11
Total Direct Costs $835,000
Funding Agency: National Cancer Institute
Title: Understanding TRAIL Sensitivity in Gliomas
• P50 CA097257 - Mitchel S. Berger, PI, Michael Prados and Russell O. Pieper Co-PI
Award Period 6/1/07 to 5/31/12
Total Direct Costs $7,728,349
Funding Agency: National Cancer Institute
Title : Brain Tumor SPORE Grant
• P50 CA097257 - Mitchel S. Berger, PI, Michael Prados and Russell O. Pieper Co-PI
Project 5: Parsa and Pieper, PIs: Heat shock protein vaccine development: glioma immunoresistance and P1(3)K/Akt/mTOR pathway activation.
Award Period 6/1/07 to 5/31/12
Total Direct Costs $7,728,349
Funding Agency: National Cancer Institute
Title : Brain Tumor SPORE Grant
A three step process adds ubiquitin to proteins and targets them for proteasomal degradation