Clinical Trials for Spinal Disorders
For more information about patients' participation in the following clinical trials, contact the UCSF Spine Center at 415.353.2739 or 1-866-SPINE. For information about spinal cord injury trials, contact Sanjay Dhall, MD at Sanjay.Dhall@ucsf.edu.
CAMPER (The Canadian Multicentre CSF Monitoring and Biomarker Study): This trial is for patients with severe (AIS A, B, C) acute traumatic spinal cord injury. This trial involves placing a lumbar intrathecal pressure monitor and collecting CSF samples. Clinicaltrials.gov Overview
Orthofix Odontoid Fracture Trial: This trial is for elderly patients with inoperable odontoid (C2) fractures and studies the efficacy of pulsed electromagnetic field generators (bone stimulators) to promote healing. Clinicaltrials.gov Overview
TRACK-SCI (Transforming Research and Clinical Knowledge in Spinal Cord Injury): This prospective study enrolls all patients with acute traumatic spinal cord injury at San Francisco General Hospital to detail acute care variables, intraoperative and ICU monitoring, immune status, and long-term outcomes. A database has been assembled to examine various predictors of impairment.
Efficacy of Riluzole in Patients with Cervical Spondylotic Myelopathy Undergoing Surgical Treatment: Riluzole is FDA-approved for the treatment of amyotrophic lateral sclerosis, which has some similar clinical features to CSM. Riluzole is currently under investigation for traumatic spinal cord injury. Given this background, there is a strong basis to consider studying the potential neurological benefits of Riluzole as a treatment to surgical decompression in patients with CSM. Clinicaltrials.gov Overview
Cervical Spondylotic Myelopathy Surgical Trial (CSM-S Trial): The purpose of the study is to determine the optimal surgical approach (ventral vs dorsal) for patients with multi-level cervical spondylotic myelopathy (CSM). Clinicaltrials.gov Overview
Prospective Evaluation of Elderly Deformity Surgery (PEEDS): This is a prospective, multicenter study that will follow outcomes for patients over the age of 60 who have undergone spinal fusion for moderate or severe spinal deformity. Quality of life and functional outcomes are measured to determine risks and outcomes in this patient population. Clinicaltrials.gov Overview
Prospective Primary Tumor Database by AOSpine Knowledge Forum Tumor: To prospectively investigate the prognostic variables (clinical, diagnostic, and therapeutic) within subgroups of patients diagnosed with primary spinal column tumors that are associated with survival, local recurrence, perioperative morbidity, and patient reported outcomes. AOSpine Knowledge Forum
National Neurosurgery Quality and Outcomes Database: national clinical registry for neurosurgical procedures and practice patterns. Its primary purpose is to track quality of surgical care for the most common neurosurgical procedures, as well as provide practice groups and hospitals with an immediate infrastructure for analyzing and reporting the quality of their neurosurgical care. NeuroPoint Alliance
Prospective, Multicenter Adult Spinal Deformity Outcomes Database Registry
Minimally Invasive Surgery for the Treatment of Adult Deformity: A Multicenter Study