Adult Brain Tumor Clinical Trials
Clinical Trials: Adult Program for the Treatment of Malignant Brain Tumors
Questions about patients' participation in the following clinical trials can be directed to the Neuro-Oncology Nursing Line by calling 415.353.2652, or by email to Valerie Kivett at kivettv@neurosurg.ucsf.edu
Adult Clinical Trials: Newly Diagnosed Malignant Glioma
A Phase II study of Bevacizumab (Avastinâ) plus Temodar and Tarceva during and after Radiation Therapy in patients with newly diagnosed Glioblastoma or Gliosarcoma
PHASE II, single-arm, open-label investigation of HSPPC-96 vaccine with concurrent temozolomide in patients with newly diagnosed Glioblastoma Multiforme
ABTC07-01 - Phase I Trial of Aflibercept (VEGF Trap) with Radiation Therapy and Concomitant and Adjuvant Temozolomide in Patients with Malignant Glioma – Arm 1
Adult Clinical Trials: Newly Diagnosed Low-Grade Glioma
A Phase I Study of Temozolomide (SCH 52365) in the Treatment of Adult Patients with Supratentorial Low-Grade Glioma
Clinical Trials: Recurrent Low-Grade Glioma
Phase II Trial of RAD001 in Patients with Recurrent Low Grade Glioma
Adult Clinical Trials: Stable Tumor
ABTC04-03 - A Phase I Study of Vorinostat (SAHA) and Temozolomide in Patients with Malignant Glioma
ABTC07-01 - Phase I Trial of Aflibercept (VEGF Trap) with Radiation Therapy and Concomitant and Adjuvant Temozolomide in Patients with Malignant Glioma - Arm 2 and Arm 3
Adult Clinical Trials: Recurrent Tumor
A Phase I trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients with Recurrent High-Grade Gliomas
Phase I/II trial of Oncophage (Heat Shock Protein Peptide Complex-96) Vaccine For Patients With Recurrent High Grade Glioma
ABTC05-02 - Phase I/II Studies of BAY 43-9006 (sorafenib) in Combination with OSI-774 (erlotinib), R115777 (tipifarnib) or CCI-779 (temsirolimus) in Patients with Recurrent Glioblastoma Multiforme or Gliosarcoma
Phase II Study Of 7 Days On/7 Days Off Temozolomide In Patients With High-Grade Glioma
A Phase 2 Study of XL184 in Subjects with Progressive or Recurrent Glioblastoma Multiforme in First or Second Relapse
CERN08-02 - A Phase II Study of Dose-Dense Temozolomide and Lapatinib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial and Spinal Cord Ependymoma
ABTC07-01 - Phase I Trial of Aflibercept (VEGF Trap) with Radiation Therapy and Concomitant and Adjuvant Temozolomide in Patients with Malignant Glioma - Arm 2 and Arm 3
Non-Chemotherapy Protocols
San Francisco Bay Area Adult Glioma Prognosis Study
A Prospective National Study to Molecularly and Genetically Characterize Human Gliomas
Adult Clinical Trials In Development
A Phase I Ascending Dose Trial of the safety and Tolerability of Toca-511 in Patients with Recurrent Glioblastoma Multiforme
A Phase I Study of MK-0752, a Notch Inhibitor, in Patients With Metastatic or Locally Advanced Breast Cancer and Other Solid Tumors
Phase II Study of Gamma-Knife Radiosurgery Using Magnetic Resonance Spectroscopy for Target Definition in Patients with Recurrent Glioma
ABTC08-01 - A Phase I/II Trial of Temozolomide and ABT-888 in Subjects with Newly Diagnosed Glioblastoma Multiforme
ABTC09-04 - A Biomarker and Phase II Study of GDC-0449 in Patients with Recurrent Glioblastoma Multiforme