Jacob Young MD

Jacob Young, MD

Expected Graduation Date: 2024

Education, Training, and Previous Positions

2012: BS, Duke University
2017: MD, University of Chicago Pritzker School of Medicine

Selected Honors and Awards

2018: Krevans Award for Excellence in Patient Care, San Francisco General Hospital
2017: Outstanding Achievement Award in Medicine, University of Chicago
2017: Peter Huttenlocher & Douglas Buchanan Prize for Best Medical Student Clinician/Researcher in Neurology, Department of Neurology, University of Chicago
2017: Departmental Award for Outstanding Performance in Surgery, Department of Surgery, University of Chicago
2017: Graduation with Honors, University of Chicago Pritzker School of Medicine
2016: Alpha Omega Alpha Honor Society, University of Chicago
2015: 3rd Place, Best Medical Student Basic Science Poster, American College of Surgeons (ACS) Clinical Congress 2015
2015: Medical Student Summer Research Fellowship, Neurosurgery Research & Education Foundation (NREF)/American Association of Neurological Surgeons (AANS)
2013: Phi Beta Kappa, Duke University
2014: The Brain Research Foundation Award for Neuroscience, University of Chicago
2012: Graduation with Distinction in Neuroscience for Senior Thesis, Duke University
2011: Neuroscience Program of Research Fellow, Duke University
2010: CT Boyd Scholarship Recipient, Delta Tau Delta Fraternity, Duke University
2010: Vertical Integration Program Fellow, Duke University, Departments of Psychology and Neuroscience

Selected Recent Publications

Moshed RA, Young JS, Han SJ, Hervey-Jumper SL, Berger MS. Clinical Outcomes in Patients Undergoing Repeat Resection of Recurrent Insular Gliomas. J Neurosurg, In Press. 

Young, JS, Bernal, G, Polster, SP, Nunez, L, Larsen, GF, Mansour, N, Podell, M, Yamini, B. Convection Enhanced Delivery of Polymeric Nanoparticles Encapsulating Chemotherapy in Canines with Spontaneous Suptratentorial Tumors. World Neurosurgery, In Press.

Dayani F, Young JS, Bonte A, Chang E, Theodosopoulos PV, McDermott MW, Berger MS Aghi MK. Safety and Outcomes After Surgical Resection for Butterfly Glioblastoma. Neurosurgical Focus. Jun 2018; 44(6):E4 PMID: 29852771

Moshed RA, Young JS, Han SJ, Hervey-Jumper SL, Berger MS. The Transcortical Equatorial Approach for Gliomas of the Mesial Temporal Lobe: Techniques and Functional Outcomes. Journal of Neurological Surgery. Apr 2018;1-9. PMID: 29676697

Magill S*, Young JS*, Chae R, Aghi MK, Theodosopoulos PV, McDermott MW. Relationship Between Tumor Location, Size, and WHO Grade in Meningioma. Neurosurgical Focus. Apr 2018; 44(4):E4. PMID: 29606048 *co-first authors

Kane JR, Panek WK, Young JS, Rashidi A, Kim JW, Lesniak MS. Hitting the Nail on the Head: Combining Oncolytic Adenovirus-Mediated Virotherapy and Immunomodulation for the Treatment of Glioma. Oncotarget. Sept 2017;8(51):89391-89405. PMID: 29179527

Young JS, Chmura SJ, Wainwright DA, Yamini B, Peters KB, Lukas RV. The Management of Glioblastoma in the Elderly. Journal of Neurological Sciences. Sept 2017;380:250-255. PMID: 28870580.

Utevsky AV, Smith DV, Young JS, Huettel SA. Large-Scale Network Coupling with the Fusiform Face Area Facilitates Future Social Motivation. eNeuro. Oct 2017; 4(5). PMID: 29034316

Kim JW, Miska J, Young JS, Rashidi A, Kane JR, Panek WK, Kanojia D, Han Y, Balyasnikova IV, Lesniak MS. A Comparative Study of Replication-Incompetent and -Competent Adenoviral Therapy-Mediated Immune Response in a Murine Glioma Model. Mol Ther Oncolytics. 2017 May 6;5:97-104.

Hobbs JG, Morshed RA, Young JS, Desai B, Mehta AI. Radiotherapy and surgical treatment of metastatic breast cancer of the spine. Clinics in Surgery: Orthopaedic Surgery. 2016; 1(1038):1-11

Young JS, Hobbs JG, Bailes JE. The Impact of Traumatic Brain Injury on the Aging Brain. Curr Psychiatry Rep. 2016 Sep;18(9):81. 

Hobbs JG, Desai B, Young JS, Polster SP, Tobin MK, Geraghty JR, Linninger AA, Ovelese AA, Shin JH, Bydon M, Mehta AI. Intramedullary spinal cord tumors: a review and discussion of surgical rationale. World Spinal Colun Journal. 2016;7(2):65-83.

Kim JW, Auffinger B, Spencer DA, Miska J, Chang AL, Kane JR, Young JS, Kanojia D, Qiao J, Mann JF, Zhang L, Wu M, Ahmed AU, Aboody KS, Strong TV, Hébert CD, Lesniak MS. Single dose GLP toxicity and biodistribution study of a conditionally replicative adenovirus vector, CRAd-S-pk7, administered by intracerebral injection to Syrian hamsters. J Transl Med. 2016 May 16;14(1):134. 

Hobbs JG, Young JS, Bailes JE. Sports-related concussions: diagnosis, complications, and current management strategies. Neurosurg Focus. 2016 Apr;40(4):E5. 

Kim JW, Young JS, Solomaha E, Kanojia D, Lesniak MS, Balyasnikova IV. A novel single-chain antibody redirects adenovirus to IL13Rα2-expressing brain tumors. Sci Rep. 2015 Dec 14;5:18133.

Kim JW, Kane JR, Young JS, Chang AL, Kanojia D, Morshed RA, Miska J, Ahmed AU, Balyasnikova IV, Han Y, Zhang L, Curiel DT, Lesniak MS. A Genetically Modified Adenoviral Vector with a Phage Display-Derived Peptide Incorporated into Fiber Fibritin Chimera Prolongs Survival in Experimental Glioma. Hum Gene Ther. 2015 Sep;26(9):635-46.

Spencer DA, Young JS, Kanojia D, Kim JW, Polster SP, Murphy JP, Lesniak MS. Unlocking the promise of oncolytic virotherapy in glioma: combination with chemotherapy to enhance efficacy. Ther Deliv. 2015;6(4):453-68. 

Young JS, Smith DV, Coutlee CG, Huettel SA. Synchrony between sensory and cognitive networks is associated with subclinical variation in autistic traits. Front Hum Neurosci. 2015 Mar 23;9:146. 

Kane JR, Miska J, Young JS, Kanojia D, Kim JW, Lesniak MS. Sui generis: gene therapy and delivery systems for the treatment of glioblastoma. Neuro Oncol. 2015 Mar;17 Suppl 2:ii24-ii36. 

Kim JW, Kane JR, Young JS, Chang AL, Kanojia D, Qian S, Spencer DA, Ahmed AU, Lesniak MS. Neural stem cell-mediated delivery of oncolytic adenovirus. Curr Protoc Hum Genet. 2015 Apr 1;85:13.11.1-9. 

Dang LC, Samanez-Larkin GR, Young JS, Cowan RL, Kessler RM, Zald DH. Caudate asymmetry is related to attentional impulsivity and an objective measure of ADHD-like attentional problems in healthy adults. Brain Struct Funct. 2016 Jan;221(1):277-86. 

Kessler RM, Seibyl J, Cowan RL, Zald DH, Young JS, Ansari MS, Stabin M. Radiation Dosimetry of (18)F-FPEB in Humans. J Nucl Med. 2014 Jul;55(7):1119-21.

Young JS, Morshed RA, Kim JW, Balyasnikova IV, Ahmed AU, Lesniak MS. Advances in stem cells, induced pluripotent stem cells, and engineered cells: delivery vehicles for anti-glioma therapy. Expert Opin Drug Deliv. 2014 Nov;11(11):1733-46. doi: 10.1517/17425247.2014.937420. Epub 2014 Jul 8. Review. PubMed PMID: 25005767. 

Young JS, Kim JW, Ahmed AU, Lesniak MS. Therapeutic cell carriers: a potential road to cure glioma. Expert Rev Neurother. 2014 Jun;14(6):651-60.