Michael Safaee MD

Michael Safaee MDExpected Graduation Date: 2021





Education, Training, and Previous Positions

2008: BS, University of California, Los Angeles, Summa Cum Laude
2014: MD, David Geffen School of Medicine at UCLA

Selected Honors and Awards

2014: Alpha Omega Alpha, David Geffen School of Medicine
2014: Gerald Levey Leadership Award, David Geffen School of Medicine
2012: Clinical and Translational Research Fellow, UCSF
2011: Doris Duke Foundation Clinical Research Fellowship, UCSF
2008: Distinguished Senior Award, UCLA Alumni Association
2008: Senior of the Year, UCLA BruinLife
2008: Phi Beta Kappa, UCLA
2008: Highest Departmental Honors, UCLA
2008: Chancellor’s Service Award, UCLA
2008: MCDB Senior Research Award, UCLA
2007: Rose and Sam Gilbert Honors Scholarship, UCLA
2004-2008: Dean’s Honors List, UCLA
2004-2008: College Honors Program, UCLA
2004-2008: Regents Scholarship, UCLA

Selected Recent Publications

Sun MZ, Oh T, Ivan ME, Clark AJ, Safaee M, Sayegh ET, Kaur G, Parsa AT, Bloch O. Survival impact of time to initiation of chemoradiotherapy after resection of newly diagnosed glioblastoma. J Neurosurg. 2015 May;122(5):1144-50.

Osorio JA, Clark AJ, Safaee M, Tate MC, Aghi MK, Parsa A, McDermott MW. Intraoperative Conversion from Endoscopic to Open Transcortical-Transventricular Removal of Colloid Cysts as a Salvage Procedure. Cureus. 2015 Feb 2;7(2):e247.

Safaee M, Parsa AT, Barbaro NM, Chou D, Mummaneni PV, Weinstein PR, Tihan T, Ames CP. Association of tumor location, extent of resection, and ncurofibromatosis status with clinical outcomes for 221 spinal nerve sheath tumors. Neurosurg Focus. 2015 Aug;39(2):E5.

Safaee M, Fakurnejad S, Bloch O, Clark AJ, Ivan ME, Sun MZ, Oh T, Phillips JJ, Parsa AT. Proportional upregulation of CD97 isoforms in glioblastoma and glioblastoma-derived brain tumor initiating cells. PLOS One 2015;10(2):e0111532.

Clark AJ, Safaee M, Oh T, Ivan ME, Parimi V, Hashizume R, Ozawa T, James CD, Bloch O, Parsa AT. Stable luciferase expression does not alter immunologic or in vivo growth properties of GL261 murine glioma cells. J Transl Med 2014;12(1):345.

Ivan ME, Safaee M, Oh T, Clark AJ, Sun MZ, Kim J, Bloch O, Jahangiri A, Phillips JJ, Aghi MK, Parsa AT. Epidermal growth factor-like module containing mucin-like hormone receptor 2 expression in gliomas [published online ahead of print September 9, 2014]. J Neurooncol. doi: 10.1007/s11060-014-1606-z.

Safaee M, Oh T, Parsa AT, McDermott MW, El-Sayed IH, Bloch O. Pigmented villonodular synovitis of the temporomandibular joint with intracranial extension [published online ahead of print April 25, 2014]. Head Neck. doi: 10.1002/hed.23717.

Sparrey CJ, Bailey JF, Safaee M, Clark AJ, Ames CP. Etiology of lumbar lordosis and its pathophysiology: A review of the evolution of lumbar lordosis, and the mechanics and biology of lumbar degeneration. Neurosrg Focus. 2014;36(5):E1.

Safaee M, Sun MZ, Oh T, Aghi MK, Berger MS, McDermott MW, Parsa AT, Bloch O. Use of hemostatic agents during meningioma resection: a potential risk factor for perioperative thromboembolic events. Clin Neurol Neurosurg. 2014;119:116-20.

Oh T, Safaee M, Sun MZ, Garcia RM, McDermott MW, Parsa AT, Bloch O. Surgical risk factors for post-operative pneumonia following meningioma resection. Clin Neurol Neurosurg. 2014;118:76-9.

Safaee M, Oh MC, Mummaneni PV, Weinstein PR, Ames CP, Chou D, Berger MS, Parsa AT, Gupta N. Surgical outcomes in pediatric spinal cord ependymomas. J Neurosurg Pediatr. 2014;13(4):393-9.

Safaee M, Clark AJ, Ivan ME, Oh MC, Bloch O, Sun MZ, Oh T, Parsa AT. CD97 is a multi-functional leukocyte receptor with distinct roles in human cancers. Int J Oncol. 2013;43:1343-1350.

Feldman W, Clark AJ, Safaee M, Ames CP, Parsa AT. Tumor control after surgery for spinal myxopapillary ependymomas: distinct outcomes in adults and children. J Neurosurg Spine. 2013;19(4):471-6.

Safaee M, Oh MC, Kim JM, Aranda D, Tarapore PE, Cage TA, Gupta N, Parsa AT. Histologic grade and extent of resection are associated with survival in pediatric spinal cord ependymomas. Childs Nerv Syst. 2013;29(11):2057-64.

Bloch O, Safaee M, Sun MZ, Butowski NA, McDermott MW, Berger MS, Aghi MK, Parsa AT. Disseminated progression of glioblastoma after treatment with bevacizumab. Clin Neurol Neurosurg. 2013;115(9):1795-801.

Bloch O, Crane CA, Kaur R, Safaee M, Rutkowski MJ, Parsa AT. Gliomas promote immunosuppression through induction of B7-H1 expression in tumor-associated macrophages. Clin Cancer Res. 2013;19(12):3165-75.

Clark AJ, Ziewacz JE, Safaee M, Lau D, Lyon R, Chou D, Weinstein PR, Ames CP, Clark JP, Mummaneni PV. Intraoperative neuromonitoring with MEP predicts post-operative neurological deficits in patients having surgery for cervical and cervicothoracic myelopathy. Neurosurg Focus. 2013;35(1):E7.

Safaee M, Clark AJ, Oh MC, Ivan ME, Bloch O, Kaur G, Sun MZ, Kim JM, Oh T, Berger MS, Parsa AT. Overexpression of CD97 confers an invasive phenotype in glioblastoma cells and is associated with decreased survival of glioblastoma patients. PLoS One. 2013;8(4):e62765.

Safaee M, Oh MC, Sughrue ME, DeLance AR, Bloch O, Sun MZ, Kaur G, Molinaro AM, Parsa AT. The relative benefit of gross total resection in adult choroid plexus papillomas. J Clin Neurosci. 2013;20(6):808-12.

Safaee M, Clark AJ, Tihan T, Parsa AT, Bloch O. Falcine and parasagittal chondrosarcomas. J Clin Neurosci. 2013;20(9):1232-6.

DeLance AR, Safaee M, Oh MC, Clark AJ, Kaur G, Sun MZ, Bollen AW, Phillips JJ, Parsa AT. Tuberculoma of the central nervous system. J Clin Neurosci. 2013;20(10):1333-41.

Safaee M, Clark AJ, Bloch O, Oh MC, Singh A, Auguste KI, Gupta N, McDermott MW, Aghi MK, Berger MS, Parsa AT. Surgical outcomes in choroid plexus papillomas: an institutional experience. J Neurooncol. 2013;113(1):117-25.

Safaee M, Oh MC, Bloch O, Sun MZ, Kaur G, Auguste KI, Tihan T, Parsa AT. Choroid plexus papillomas: Advances in molecular biology and understanding of tumorigenesis. Neuro Oncol. 2013;15(3):255-67.

Hauptman JS, Barkhoudarian G, Safaee M, Gorgulho A, Tenn S, Agazaryan N, Selch M, De Salles AA. Challenges in linear accelerator radiotherapy for chordomas and chondrosarcomas of the skull base: Focus on complications. Int J Radiat Oncol Biol Phys. 2012;83(2):542-51.

Oh MC, Kim JM, Safaee M, Kaur G, Sun MZ, Kaur R, Celli A, Mauro TM, Parsa AT. Overexpression of calcium-permeable glutamate receptors in glioblastoma derived brain tumor initiating cells compared to differentiated tumor cells. PLoS One. 2012;7(10):e47846.