Ramin Morshed MD

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Expected Graduation Date: 2023




Education, Training, and Previous Positions

2011: BS, University of California, Los Angeles
2016: MD, Pritzker School of Medicine at the University of Chicago

Selected Honors and Awards

2016: Peter Huttenlocher and Doughlas Buchanan Prize in Neurology
2016: John Van Prohaska Award
2015: Alpha Omega Alpha Honor Medical Society
2013 –2014: Howard Hughes Medical Institute Medical Research Fellow
2014: Poster Award at Charles B. Huggins Annual Research Symposium
2012: Pritzker Summer Research Program Award for Basic Science Project
2012: AANS Medical Student Summer Research Fellow
2012: Northwestern CCNE Medical Student Summer Research Fellow
2011: Dean’s Prize at the UCLA Science Poster Day
2011: Top Research Award at the UCLA Neuroscience Poster Day

Recent Publications

Morshed RA, Muroski ME, Dai Q, Wegscheid ML, Auffinger B, Yu D, Han Y, Zhang L, Wu M, Cheng Y, Lesniak MS. Cell-Penetrating Peptide-Modified Gold Nanoparticles for the Delivery of Doxorubicin to Brain Metastatic Breast Cancer. Mol Pharm. 2016 Jun 6;13(6):1843-54. doi: 10.1021/acs.molpharmaceut.6b00004. Epub 2016 May 23. PubMed PMID: 27169484.

Cahill KE, Morshed RA, Yamini B. Nuclear factor-κB in glioblastoma: insights into regulators and targeted therapy. Neuro Oncol. 2016 Mar;18(3):329-39. doi: 10.1093/neuonc/nov265. Epub 2015 Nov 2. Review. PubMed PMID: 26534766; PubMed Central PMCID: PMC4767244.

Cheng SH, Yu D, Tsai HM, Morshed RA, Kanojia D, Lo LW, Leoni L, Govind Y, Zhang L, Aboody KS, Lesniak MS, Chen CT, Balyasnikova IV. Dynamic In Vivo SPECT Imaging of Neural Stem Cells Functionalized with Radiolabeled Nanoparticles for Tracking of Glioblastoma. J Nucl Med. 2016 Feb;57(2):279-84. doi: 10.2967/jnumed.115.163006. Epub 2015 Nov 12. PubMed PMID: 26564318.

Cheng Y, Muroski ME, Petit DC, Mansell R, Vemulkar T, Morshed RA, Han Y, Balyasnikova IV, Horbinski CM, Huang X, Zhang L, Cowburn RP, Lesniak MS. Rotating magnetic field induced oscillation of magnetic particles for in vivo mechanical destruction of malignant glioma. J Control Release. 2016 Feb 10;223:75-84. doi: 10.1016/j.jconrel.2015.12.028. Epub 2015 Dec 19. PubMed PMID: 26708022; PubMed Central PMCID: PMC4724455.

Muroski ME, Morshed RA, Cheng Y, Vemulkar T, Mansell R, Han Y, Zhang L, Aboody KS, Cowburn RP, Lesniak MS. Controlled Payload Release by Magnetic Field Triggered Neural Stem Cell Destruction for Malignant Glioma Treatment. PLoS One. 2016 Jan 6;11(1):e0145129. doi: 10.1371/journal.pone.0145129. eCollection 2016. PubMed PMID: 26734932; PubMed Central PMCID: PMC4703386.

Kim JW, Morshed RA, Kane JR, Auffinger B, Qiao J, Lesniak MS. Viral Vector Production: Adenovirus. Methods Mol Biol. 2016;1382:115-30. doi: 10.1007/978-1-4939-3271-9_9. PubMed PMID: 26611583.

Kanojia D, Balyasnikova IV, Morshed RA, Frank RT, Yu D, Zhang L, Spencer DA, Kim JW, Han Y, Yu D, Ahmed AU, Aboody KS, Lesniak MS. Neural Stem Cells Secreting Anti-HER2 Antibody Improve Survival in a Preclinical Model of HER2 Overexpressing Breast Cancer Brain Metastases. Stem Cells. 2015 Oct;33(10):2985-94. doi: 10.1002/stem.2109. Epub 2015 Aug 11. PubMed PMID: 26260958; PubMed Central PMCID: PMC4578995.

Kim JW, Kane JR, Young JS, Chang AL, Kanojia D, Morshed RA, Miska J, Ahmed AU, Balyasnikova IV, Han Y, Zhang L, Curiel DT, Lesniak MS. A Genetically Modified Adenoviral Vector with a Phage Display-Derived Peptide Incorporated into Fiber Fibritin Chimera Prolongs Survival in Experimental Glioma. Hum Gene Ther. 2015 Sep;26(9):635-46. doi: 10.1089/hum.2015.008. Epub 2015 Aug 11. PubMed PMID: 26058317; PubMed Central PMCID: PMC4575547.

Kanojia D, Morshed RA, Zhang L, Miska JM, Qiao J, Kim JW, Pytel P, Balyasnikova IV, Lesniak MS, Ahmed AU. βIII-Tubulin Regulates Breast Cancer Metastases to the Brain. Mol Cancer Ther. 2015 May;14(5):1152-61. doi: 10.1158/1535-7163.MCT-14-0950. Epub 2015 Feb 27. PubMed PMID: 25724666; PubMed Central PMCID: PMC4425587.

Morshed RA, Gutova M, Juliano J, Barish ME, Hawkins-Daarud A, Oganesyan D, Vazgen K, Yang T, Annala A, Ahmed AU, Aboody KS, Swanson KR, Moats RA, Lesniak MS. Analysis of glioblastoma tumor coverage by oncolytic virus-loaded neural stem cells using MRI-based tracking and histological reconstruction. Cancer Gene Ther. 2015 Jan;22(1):55-61. doi: 10.1038/cgt.2014.72. Epub 2014 Dec 19. PubMed PMID: 25525033; PubMed Central PMCID: PMC4293243.

Cheng Y, Dai Q, Morshed RA, Fan X, Wegscheid ML, Wainwright DA, Han Y, Zhang L, Auffinger B, Tobias AL, Rincón E, Thaci B, Ahmed AU, Warnke PC, He C, Lesniak MS. Blood-brain barrier permeable gold nanoparticles: an efficient delivery platform for enhanced malignant glioma therapy and imaging. Small. 2014 Dec 29;10(24):5137-50. doi: 10.1002/smll.201400654. Epub 2014 Aug 8. PubMed PMID: 25104165; PubMed Central PMCID: PMC4268041.

Young JS, Morshed RA, Kim JW, Balyasnikova IV, Ahmed AU, Lesniak MS. Advances in stem cells, induced pluripotent stem cells, and engineered cells: delivery vehicles for anti-glioma therapy. Expert Opin Drug Deliv. 2014 Nov;11(11):1733-46. doi: 10.1517/17425247.2014.937420. Epub 2014 Jul 8. Review. PubMed PMID: 25005767.

Morshed RA, Cheng Y, Auffinger B, Wegscheid ML, Lesniak MS. The potential of polymeric micelles in the context of glioblastoma therapy. Front Pharmacol. 2013 Dec 30;4:157. doi: 10.3389/fphar.2013.00157. Review. PubMed PMID: 24416018; PubMed Central PMCID: PMC3874582.

Cheng Y, Morshed R, Cheng SH, Tobias A, Auffinger B, Wainwright DA, Zhang L, Yunis C, Han Y, Chen CT, Lo LW, Aboody KS, Ahmed AU, Lesniak MS. Nanoparticle-programmed self-destructive neural stem cells for glioblastoma targeting and therapy. Small. 2013 Dec 20;9(24):4123-9. doi: 10.1002/smll.201301111. Epub 2013 Jul 21. PubMed PMID: 23873826; PubMed Central PMCID: PMC3879136.

Chung EJ, Cheng Y, Morshed R, Nord K, Han Y, Wegscheid ML, Auffinger B, Wainwright DA, Lesniak MS, Tirrell MV. Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma. Biomaterials. 2014 Jan;35(4):1249-56. doi: 10.1016/j.biomaterials.2013.10.064. Epub 2013 Nov 7. PubMed PMID: 24211079; PubMed Central PMCID: PMC3880134.

Auffinger B, Morshed R, Tobias A, Cheng Y, Ahmed AU, Lesniak MS. Drug-loaded nanoparticle systems and adult stem cells: a potential marriage for the treatment of malignant glioma? Oncotarget. 2013 Mar;4(3):378-96. Review. PubMed PMID: 23594406; PubMed Central PMCID: PMC3717302.

Wegscheid ML, Morshed RA, Cheng Y, Lesniak MS. The art of attraction: applications of multifunctional magnetic nanomaterials for malignant glioma. Expert Opin Drug Deliv. 2014 Jun;11(6):957-75. doi: 10.1517/17425247.2014.912629. Epub 2014 Apr 25. Review. PubMed PMID: 24766329.

Cheng Y, Morshed RA, Auffinger B, Tobias AL, Lesniak MS. Multifunctional nanoparticles for brain tumor imaging and therapy. Adv Drug Deliv Rev. 2014 Feb;66:42-57. doi: 10.1016/j.addr.2013.09.006. Epub 2013 Sep 20. Review. PubMed PMID: 24060923; PubMed Central PMCID: PMC3948347.