Darryl Lau MD

Darryl Lau MD - UCSF Neurosurgery

Expected Graduation Date: 2020




Education, Training, and Previous Positions

2008: BA, University of California, Berkeley, Summa Cum Laude
2013: MD, University of Michigan Medical School, Summa Cum Laude

Selected Honors and Awards

2017: Andrew T. Parsa Research Fellowship, Neurosurgery Research & Education Foundation
2016: Charlie Kuntz Scholar Award, AANS/CNS Joint Section on Disorders of the Spine and Peripheral Nerves
2015: Styrker Neuro-Oncology Award, Annual Meeting of the American Association of Neurological Surgeons
2013: Dean’s Award for Research Excellence, University of Michigan Medical School
2013: Graduation with Distinction in Research, University of Michigan Medical School
2012: Dean’s Commendation for Excellence in Clinical Skills and the Art of Medicine Award, University of Michigan Medical School
2012: Alpha Omega Alpha Medical Honor Society
2012: Farhat Medical Student Research Fellowship, University of Michigan Medical School
2011: Academic University Grant, University of Michigan Medical School
2011: Albert M. Barret Award for Academic and Clinical Excellence in Psychiatry, University of Michigan Medical School
2010: Student Biomedical Research Program Certificate of Research Excellence, University of Michigan Medical School
2010: Student Biomedical Research Program Grant, University of Michigan Medical School
2010: Alpha Omega Alpha Carolyn L. Kuckein Research Fellowship
2008: Franklin M. Henry Award for Outstanding Research Achievement, University of California, Berkeley

Recent Publications

Lau D, Chou D. Minimally invasive instrumentation without fusion during posterior thoracic corpectomies: a comparison of percutaneously instrumented nonfused segments with open instrumented fused segments. J Neurosurg Spine. 2017 Apr 21:1-7.

Niu T, Lu DS, Yew A, Lau D, Hoffman H, McArthur D, Chou D, Lu DC. Postoperative Cerebrospinal Fluid Leak Rates with Subfascial Epidural Drain Placement after Intentional Durotomy in Spine Surgery. Global Spine J. 2016 Dec;6(8):780-785.

Lau D, Chou D. 350 Mini-open Transpedicular Corpectomy and Percutaneous Instrumentation Without Fusion: Reoperation Rates for Implant Failure and Pseudarthrosis. Neurosurgery. 2016 Aug;63 Suppl 1:203.

Lau D, Winkler EA, Than KD, Chou D, Mummaneni PV. 169 Laminoplasty vs Laminectomy With Posterior Spinal Fusion for Multilevel Cervical Spondylotic Myelopathy: Matched Cohorts of Regional Sagittal Balance. Neurosurgery. 2016 Aug;63 Suppl 1:167-8.

Magill ST, Lau D, Raleigh DR, Sneed PK, Fogh SE, McDermott MW. Surgical Resection and Interstitial Iodine-125 Brachytherapy for High-Grade Meningiomas: A 25-Year Series. Neurosurgery. 2016 Jun 1. [Epub ahead of print].

Lau D, Chan AK, Theologis AA, Chou D, Mummaneni PV, Burch S, Berven S, Deviren V, Ames C. Costs and readmission rates for the resection of primary and metastatic spinal tumors: a comparative analysis of 181 patients. J Neurosurg Spine. 2016 Sep;25(3):366-78.

Theologis AA, Miller L, Callahan M, Lau D, Zygourakis C, Scheer JK, Burch S, Pekmezci M, Chou D, Tay B, Mummaneni P, Berven S, Deviren V, Ames CP. Economic Impact of Revision Surgery for Proximal Junctional Failure After Adult Spinal Deformity Surgery: A Cost Analysis of 57 Operations in a 10-year Experience at a Major Deformity Center. Spine (Phila Pa 1976). 2016 Aug 15;41(16):E964-72.

Chang EF, Breshears JD, Raygor KP, Lau D, Molinaro AM, Berger MS. Stereotactic probability and variability of speech arrest and anomia sites during stimulation mapping of the language dominant hemisphere. J Neurosurg. 2016 Feb 19:1-8. [Epub ahead of print].

Lau D, Funao H, Clark AJ, Nicholls F, Smith J, Bess S, Shaffrey C, Schwab FJ, Lafage V, Deviren V, Hart R, Kebaish KM, Ames CP; International Spine Study Group. The Clinical Correlation of the Hart-ISSG Proximal Junctional Kyphosis Severity Scale With Health-Related Quality-of-life Outcomes and Need for Revision Surgery. Spine (Phila Pa 1976). 2016 Feb;41(3):213-23.

Lau D, Hervey-Jumper SL, Chang S, Molinaro AM, McDermott MW, Phillips JJ, Berger MS. A prospective Phase II clinical trial of 5-aminolevulinic acid to assess the correlation of intraoperative fluorescence intensity and degree of histologic cellularity during resection of high-grade gliomas. J Neurosurg. 2016 May;124(5):1300-9.

Hervey-Jumper SL, Li J, Osorio JA, Lau D, Molinaro AM, Benet A, Berger MS. Surgical assessment of the insula. Part 2: validation of the Berger-Sanai zone classification system for predicting extent of glioma resection. J Neurosurg. 2016 Feb;124(2):482-8.

Lau D, McDermott MW. A Method for Combining Thin and Thick Malleable Titanium Mesh in the Repair of Cranial Defects. Cureus. 2015 May 5;7(5):e267.

Lau D, Chou D, Mummaneni PV. Two-level corpectomy versus three-level discectomy for cervical spondylotic myelopathy: a comparison of perioperative, radiographic, and clinical outcomes. J Neurosurg Spine. 2015 Sep;23(3):280-9.

Lau D, Ziewacz JE, Le H, Wadhwa R, Mummaneni PV. A controlled anterior sequential interbody dilation technique for correction of cervical kyphosis. J Neurosurg Spine. 2015 Sep;23(3):263-73.

Lau D, Chou D. Posterior thoracic corpectomy with cage reconstruction for metastatic spinal tumors: comparing the mini-open approach to the open approach. J Neurosurg Spine. 2015 Aug;23(2):217-27.

Hervey-Jumper SL, Li J, Lau D, Molinaro AM, Perry DW, Meng L, Berger MS. Awake craniotomy to maximize glioma resection: methods and technical nuances over a 27-year period. J Neurosurg. 2015 Aug;123(2):325-39.

Scheer JK, Fakurnejad S, Lau D, Daubs MD, Coe JD, Paonessa KJ, LaGrone MO, Amaral RA, Trobisch PD, Lee JH, Fabris-Monterumici D, Anand N, Cree AK, Hart RA, Hey LA, Ames CP; SRS Adult Spinal Deformity Committee. Results of the 2014 SRS Survey on PJK/PJF: A Report on Variation of Select SRS Member Practice Patterns, Treatment Indications, and Opinions on Classification Development. Spine (Phila Pa 1976). 2015 Jun 1;40(11):829-40.

Potts MB, Lau D, Abla AA, Kim H, Young WL, Lawton MT; UCSF Brain AVM Study Project. Current surgical results with low-grade brain arteriovenous malformations. J Neurosurg. 2015 Apr;122(4):912-20.

Lau D, Rutledge C, Aghi MK. Cushing's disease: current medical therapies and molecular insights guiding future therapies. Neurosurg Focus. 2015 Feb;38(2):E11.

Lau D, Magill ST, Aghi MK. Molecularly targeted therapies for recurrent glioblastoma: current and future targets. Neurosurg Focus. 2014 Dec;37(6):E15.

Park P, Lau D, Brodt ED, Dettori JR. Electrical stimulation to enhance spinal fusion: a systematic review. Evid Based Spine Care J. 2014 Oct;5(2):87-94.

Lau D, Yee TJ, La Marca F, Patel R, Park P. Utility of the Surgical Apgar Score for Patients who Undergo Surgery for Spinal Metastasis. J Spinal Disord Tech. 2014 Oct 10. [Epub ahead of print] PubMed PMID: 25310396.

Lau D, Clark AJ, Scheer JK, Daubs MD, Coe JD, Paonessa KJ, LaGrone MO, Kasten MD, Amaral RA, Trobisch PD, Lee JH, Fabris-Monterumici D, Anand N, Cree AK, Hart RA, Hey LA, Ames CP; SRS Adult Spinal Deformity Committee. Proximal junctional kyphosis and failure after spinal deformity surgery: a systematic review of the literature as a background to classification development. Spine (Phila Pa 1976). 2014 Dec 1;39(25):2093-102.

Lau D, Moon DH, Park P, Hervey-Jumper S, McKeever PE, Orringer DA. Radiation-induced intradural malignant peripheral nerve sheath tumor of the cauda equina with diffuse leptomeningeal metastasis. J Neurosurg Spine. 2014 Nov;21(5):719-26.

Wadhwa R, Mummaneni PV, Lau D, Le H, Chou D, Dhall SS. Perioperative morbidity and mortality comparison in circumferential cervical fusion for osteomyelitis versus cervical spondylotic myelopathy. Neurosurg Focus. 2014 Aug;37(2):E7.

Lau D, Chou D, Ziewacz JE, Mummaneni PV. The effects of smoking on perioperative outcomes and pseudarthrosis following anterior cervical corpectomy: Clinical article. J Neurosurg Spine. 2014 Oct;21(4):547-58.

Leach MR, Lau D, La Marca F, Park P. Outcomes after surgery for spinal metastasis of colorectal origin: case series. Asian Spine J. 2014 Jun;8(3):267-72.

Hervey-Jumper SL, Garton HJ, Lau D, Altshuler D, Quint DJ, Robertson PL, Muraszko KM, Maher CO. Differences in vascular endothelial growth factor receptor expression and correlation with the degree of enhancement in medulloblastoma. J Neurosurg Pediatr. 2014 Aug;14(2):121-8.

Lau D, Barker FG 2nd, Aghi MK. Awards, lectures, and fellowships sponsored by the AANS/CNS Section on Tumors. J Neurooncol. 2014 Sep;119(3):583-91.

Wang DD, Lau D, Rolston JD, Englot DJ, Sneed PK, McDermott MW. Pain experience using conventional versus angled anterior posts during stereotactic head frame placement for radiosurgery. J Clin Neurosci. 2014 Sep;21(9):1538-42.

Saigal R, Lau D, Wadhwa R, Le H, Khashan M, Berven S, Chou D, Mummaneni PV. Unilateral versus bilateral iliac screws for spinopelvic fixation: are two screws better than one? Neurosurg Focus. 2014 May;36(5):E10.

Terman SW, Yee TJ, Lau D, Khan AA, La Marca F, Park P. Minimally invasive versus open transforaminal lumbar interbody fusion: comparison of clinical outcomes among obese patients. J Neurosurg Spine. 2014 Jun;20(6):644-52.

Lau D, Than KD, La Marca F, Park P. Independent predictors for local recurrence following surgery for spinal metastasis. Acta Neurochir (Wien). 2014 Feb;156(2):277-82.

Chou D, Lau D, Roy E. Feasibility of the mini-open vertebral column resection for severe thoracic kyphosis. J Clin Neurosci. 2014 May;21(5):841-5.

Lau D, Shin SS, Patel R, Park P. Treatment of C2 body fracture with unusual distractive and rotational components resulting in gross instability. World J Orthop. 2013 Oct 18;4(4):323-6.

Lau D, Maa J, Mummaneni PV, Chou D. Holospinal epidural abscess. J Clin Neurosci. 2014 Mar;21(3):517-20.

Lau D, Yarlagadda J, Jahan T, Jablons D, Chou D. Desmoplastic fibroma of the spine causing severe mediastinal compression and brachial plexus encasement: report of 2 cases. J Neurosurg Spine. 2013 Oct;19(4):515-20.

Lau D, Khan A, Terman SW, Yee T, La Marca F, Park P. Comparison of perioperative outcomes following open versus minimally invasive transforaminal lumbar interbody fusion in obese patients. Neurosurg Focus. 2013 Aug;35(2):E10.

Clark AJ, Ziewacz JE, Safaee M, Lau D, Lyon R, Chou D, Weinstein PR, Ames CP, Clark JP 3rd, Mummaneni PV. Intraoperative neuromonitoring with MEPs and prediction of postoperative neurological deficits in patients undergoing surgery for cervical and cervicothoracic myelopathy. Neurosurg Focus 2013;35(1):E7.

Lau D, Berger MS, Khullar D, Maa J. The impact of smoking on neurosurgical outcomes [published online ahead of print June 18, 2013]. J Neurosurg. doi: 10.3171/2013.5.JNS122287.

Lau D, Leach MR, Than KD, Ziewacz J, La Marca F, Park P. Independent predictors of complication following surgery for spinal metastasis. Eur Spine J 2013;22(6):1402-7.

Lau D, Song Y, Guan Z, La Marca F, Park P. Radiologic outcomes of static versus expandable titanium cages after corpectomy: a retrospective cohort analysis of subsidence. Neurosurgery 2013;72(4):529-39.

Lau D, Terman SW, Patel R, La Marca F, Park P. Incidence of and risk factors for superior facet violation in minimally invasive versus open pedicle screw placement during transforaminal lumbar interbody fusion: a comparative analysis. J Neurosurg Spine 2013;18(4):356-61.

Lau D, Song Y, Guan Z, Sullivan S, Marca FL, Park P. Perioperative characteristics, complications, and outcomes of single-level versus multi-level thoracic corpectomies via modified costotransversectomy approach. Spine (Phila Pa 1976) 2013;38(6):523-30.

Lau D, La Marca F, Camelo-Piragua S, Park P. Metastatic paraganglioma of the spine: Case report and review of the literature. Clin Neurol Neurosurg. 2013 Feb 8. [Epub ahead of print]

Ziewacz JE, Davis MC, Lau D, El-Sayed AM, Regenbogen SE, Sullivan SE, Mashour GA. Validation of the surgical Apgar score in a neurosurgical patient population. J Neurosurg 2013;118(2):270-9.

Lau D, Ziewacz J, Park P. Minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis in patients with significant obesity. J Clin Neurosci 2013;20(1):80-3.

Lau D, Rowland N, Devasagaya S, McDermott M. Recession of Ommaya Reservoir improves cosmesis in patients undergoing intrathecal chemotherapy for leptomeningeal disease: a technical note. Cureus 2012;4(11): e66. doi:10.7759/cureus.66

Lau D, Leach MR, La Marca F, Park P. Independent predictors of survival and the impact of repeat surgery in patients undergoing surgical treatment of spinal metastasis. J Neurosurg Spine 2012;17(6):565-76.

Ettinger RE, Oppenheimer AJ, Lau D, Hassan F, Newman MH, Buchman SR, Kasten SJ. Obstructive sleep apnea after dynamic sphincter pharyngoplasty. J Craniofac Surg 2012;23(7 Suppl 1):S32-4.

Wu C, Orringer DA, Lau D, Fletcher JJ. Cumulative incidence and predictors of neurosurgical interventions following non-severe traumatic brain injury with mildly abnormal head imaging findings. J Trauma Acute Care Surg 2012;73(5):1247-53.

Orringer D, Lau D (co-first), Khatri S, Zamora-Berridi GJ, Zhang K, Wu C, Chaudhary N, Sagher O. Extent of resection in patients with glioblastoma: limiting factors, perception of resectability, and effect on survival. J Neurosurg 2012;117(5):851-9.

Ziewacz JE, Lau D, La Marca F, Park P. Outcomes after surgery for spinal metastatic leiomyosarcoma. J Neurosurg Spine 2012;17(5):432-7.

Lau D, Harte SE, Morrow TJ, Wang S, Mata M, Fink DJ. Herpes Simplex Virus vector mediated expression of interleukin-10 reduces below-level central neuropathic pain after spinal cord injury. Neurorehabil Neural Repair 2012;26(7):889-97.

Lau D, Ziewacz JE, Siddiqi HK, Pelly A, Sullivan SE, El-Sayed AM. Cigarette smoking: a risk factor for postoperative morbidity and 1-year mortality following craniotomy for tumor resection. J Neurosurg 2012;116(6):1204-14.

Lau D, Oppenheimer AJ, Buchman S, Berger M, Kasten SJ. Posterior pharyngeal fat grafting for velopharyngeal insufficiency. Cleft Palate Craniofac J 2013;50(1):51-8.

Lau D, El-Sayed AM, Ziewacz JE, Jayachandran P, Huq FS, Zamora-Berridi GJ, Davis MC, Sullivan SE. Postoperative outcomes following closed head injury and craniotomy for evacuation of hematoma in patients older than 80 years. J Neurosurg 2012;116(1):234-45.

Lau D and Park P. Delayed C5 palsy after laminectomy and fusion for ossification of the posterior longitudinal ligament. J Spine [serial on the internet] 2012;1:104. Accessed on August 8, 2013 at: http://www.omicsgroup.org/journals/2165-7939/2165-7939-1-104.pdf.

El-Sayed AM, Ziewacz JE, Davis MC, Lau D, Siddiqi HK, Zamora-Berridi GJ, Sullivan SE. Insurance status and inequalities in outcomes after neurosurgery. World Neurosurg 2011;76(5):459-466.

Chou D, Lau D, Skelly A, Ecker E. Dynamic stabilization versus fusion for the treatment of degenerative spine conditions. Evidence-Based Spine-Care Journal 2011; 2(3):33-42.

McAllister SD, Murase R, Christian RT, Lau D, Zielinski AJ, Allison J, Almanza C, Pakdel A, Lee J, Limbad C, Liu Y, Debs RJ, Moore DH, Desprez PY. Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. Breast Cancer Res Treat 2011;129(1):37-47.

Lau D, Lee JG, Han SJ, Lu DC, Chou D. Complications and perioperative factors associated with learning the technique of minimally invasive transforaminal lumbar interbody fusion (TLIF). J Clin Neurosci 2011;18(5):624-7.

Han SJ, Lau D, Lu DC, Theodore P, Chou D. Anterior thoracolumbar corpectomies: approach morbidity with and without an access surgeon. Neurosurgery 2011;68(5):1220-6.

Lau D, Lin J, Park P. Cranial nerve III palsy resulting from intracranial hypotension caused by cerebrospinal fluid leak after paraspinal tumor resection: etiology and treatment options. Spine J 2011;11(4):e10-13.

Chou D, Lau D, Hermsmeyer J, Norvell D. Efficacy of interspinous device versus surgical decompression in the treatment of lumbar spinal stenosis: a modified network analysis. Evid Based Spine Care J 2011;2(1):45-56.

Lau D, Han SJ, Lee JG, Lu DC, Chou D. Minimally invasive compared to open microdiscectomy for lumbar disc herniation. J Clin Neurosci 2011;18(1):81-4.

Lu DC, Lau D, Lee JG, Chou D. The transpedicular approach compared with the anterior approach: an analysis of 80 thoracolumbar corpectomies. J Neurosurg Spine 2010;12(5):583-91.

Marcu JP, Christian RT, Lau D, Zielinski AJ, Horowitz MP, Lee J, Pakdel A, Allison J, Limbad C, Moore DH, Yount GL, Desprez PY, McAllister SD. Cannabidiol enhances the inhibitory effects of Δ9-Tetrahydrocannabinol on human glioblastoma cell proliferation and survival. Mol Cancer Ther 2010;9(1):180-9.