Jonathan Breshears MD


Expected Graduation Date: 2018





Education, Training, and Previous Positions

2007: BS, Biomedical Engineering, Washington University in St. Louis, Magna Cum Laude
2012: MD, Washington University in St. Louis School of Medicine
2012: MA, Washington University in St. Louis, Division of Biology & Biomedical Sciences

Professional Memberships

Congress of Neurological Surgeons
American Association of Neurological Surgeons
Society for Neuroscience

Selected Honors and Awards

2012: Brookings Prize for Medical Student Research
2009: Doris Duke Clinical Research Fellowship
2007: NCAA Div. III Men’s Basketball National Championships 3rd place
2007: Robert L. Pearce Award, Washington University Men's Basketball
2006: Tau Beta Pi, National Engineering Honor Society
2006: Alpha Eta Mu Beta Biomedical Engineering Honor Society
2004: Dean’s Scholarship, Washington University in St. Louis School of Engineering

Selected Recent Publications

Chang EF, Breshears JD, Raygor KP, Lau D, Molinaro AM, Berger MS. Stereotactic probability and variability of speech arrest and anomia sites during stimulation mapping of the language dominant hemisphere. J Neurosurg. 2016 Feb 19:1-8. [Epub ahead of print] .

Osorio JA, Breshears JD, Arnaout O, Simon NG, Hastings-Robinson AM, Aleshi P, Kliot M. Ultrasound-guided percutaneous injection of methylene blue to identify nerve pathology and guide surgery. Neurosurg Focus. 2015;39(3):E2.

Abla AA, McDougall CM, Breshears JD, Lawton MT. Intracranial-to-intracranial bypass for posterior inferior cerebellar artery aneurysms: options, technical challenges, and results in 35 patients. J Neurosurg. 2016;124(5):1275-86.

Breshears JD, Rutkowski MJ, McDermott MW, Cha S, Tihan T, Theodosopoulos PV. Surgical Management of Intracranial Neuroenteric Cysts: The UCSF Experience. J Neurol Surg B Skull Base. 2015;76(6):475-9.

Breshears JD, Molinaro AM, Chang EF. A probabilistic map of the human ventral sensorimotor cortex using electrical stimulation. J Neurosurg. 2015 Aug;123(2):340-9.

Rutkowski MJ, Breshears JD, Kunwar S, Aghi MK, Blevins LS. Approach to the postoperative patient with Cushing's disease. Pituitary. 2015 Apr;18(2):232-7.

Breshears JD, Ivan ME, Cotter JA, Bollen AW, Theodosopoulos PV, Berger MS. Primary glioblastoma of the trigeminal nerve root entry zone: case report. J Neurosurg. 2015 Jan;122(1):78-81.

Hervey-Jumper SL, Breshears J, Berger MS. Gelfoam scaffold for vein prolapse during brain tumor surgery. World Neurosurg. 2014 Nov;82(5):912.e11-3.

Freudenburg ZV, Gaona CM, Sharma M, Bundy DT, Breshears JD, Pless RB, Leuthardt EC. Fast-scale network dynamics in human cortex have specific spectral covariance patterns. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4602-7.

Mitchell TJ, Hacker CD, Breshears JD, Szrama NP, Sharma M, Bundy DT, Pahwa M, Corbetta M, Snyder AZ, Shimony JS, Leuthardt EC. A novel data-driven approach to preoperative mapping of functional cortex using resting-state functional magnetic resonance imaging. Neurosurgery. 2013 Dec;73(6):969-82; discussion 982-3.

Breshears JD, Jiang B, Rowland NC, Kunwar S, Blevins LS. Use of conivaptan for management of hyponatremia following surgery for Cushing's disease. Clin Neurol Neurosurg. 2013 Nov;115(11):2358-61.

Roland JL, Hacker CD, Breshears JD, Gaona CM, Hogan RE, Burton H, Corbetta M, Leuthardt EC. Brain mapping in a patient with congenital blindness - a case for multimodal approaches. Front Hum Neurosci. 2013 Jul 31;7:431.

Leuthardt EC, Roland J, Breshears J, Bandt SK, Shimony JS. Listening to the brain: new techniques in intraoperative brain mapping. Neurosurgery. 2013 Aug;60 Suppl 1:64-9.

10: Englot DJ, Breshears JD, Sun PP, Chang EF, Auguste KI. Seizure outcomes after resective surgery for extra-temporal lobe epilepsy in pediatric patients. J Neurosurg Pediatr. 2013 Aug;12(2):126-33.

Leuthardt EC, Pei XM, Breshears J, Gaona C, Sharma M, Freudenberg Z, Barbour D, Schalk G. Temporal evolution of gamma activity in human cortex during an overt and covert word repetition task. Front Hum Neurosci. 2012 May 3;6:99.

Rowland NC, Breshears J, Chang EF. Neurosurgery and the dawning age of Brain-Machine Interfaces. Surg Neurol Int. 2013 Mar 19;4(Suppl 1):S11-4. doi: 10.4103/2152-7806.109182. Print 2013. PubMed PMID: 23653884; PubMed Central PMCID: PMC3642748.

Breshears JD, Gaona CM, Roland JL, Sharma M, Bundy DT, Shimony JS, Rashid S, Eisenman LN, Hogan RE, Snyder AZ, Leuthardt EC. Mapping sensorimotor cortex using slow cortical potential resting state networks while awake and under anesthesia. Neurosurgery 2012;71(2):305-316

Leuthardt EC, Pei XM, Breshears JD, Gaona MS, Sharma M, Freudenberg ZV, Barbour D, Schalk G. Temporal evolution of gamma activity in human cortex during an overt and covert word repetition task. Front Hum Neurosci 2012;6:99.

Roland JL, Miller K, Freudenburg ZV, Sharma M, Smyth MD, Gaona CM, Breshears JD, Corbetta M, Leuthardt EC. The effect of age on human motor electrocortigraphic signals and implications for brain-computer interface applications. J Neural Eng 2011;8(4):046013.

Breshears JD, Gaona CM, Roland JL, Sharma M, Bundy DT, Freudenburg ZV, Limbrick DD, Smyth MD, Smart W, Leuthardt EC. Decoding Motor Signals From the Pediatric Cortex: Implications for Brain-Computer Interfaces in Children. Pediatrics 2011;128(1):e160-8.

Leuthardt EC, Gaona CM, Breshears JD, Sharma M, Roland JL, Szrama N, Solis JM, Freudenburg ZF, Schalk G. Using the electrocorticographic speech network to control a brain-computer interface in humans. J Neural Eng 2011;8(3):036004.

Gaona CM, Sharma M, Freudenburg ZV, Breshears JD, Bundy DT, Roland JL, Barbour D, Schalk G, Leuthardt EC. Nonuniform high-gamma (60-500 Hz) power changes dissociate cognitive task and anatomy in human cortex. J Neurosci 2011;31(6):2091-100.

Breshears JD, Roland J, Sharma M, Gaona C, Freudenburg Z, Tempelhoff R, Avidan MS, Leuthardt EC. Stable and dynamic cortical electrophysiology of induction and emergence with propofol anesthesia. Proc Natl Acad Sci U S A. 2010;107(49):21170-5.

Wu M, Wisneski K, Schalk G, Sharma M, Roland J, Breshears J, Gaona C, Leuthardt E. Electrocorticographic frequency alteration mapping for extraoperative localization of speech cortex. Neurosurgery 2010;66(2):E407-9.

Liu Y, Sharma M, Gaona CM, Breshears JD, Roland JL, Freudenburg ZV, Weinberger KQ, Leuthardt EC. Decoding Ipsilateral Finger Movements from ECoG Signals in Humans. Neural Information Processing Systems (NIPS) Conference Proceedings 2010. Vancouver, B.C., Canada.

Breshears J, Sharma M, Anderson N, Rashid S, Leuthardt E. Electrocorticographic frequency alteration mapping of speech cortex during an awake craniotomy: case report. Stereotact Funct Neurosurg 2010;88(1):11-5.