Philip Theodosopoulos MD


Professor and Vice Chair of Neurological Surgery

Reza and Georgianna Khatib Endowed Chair in Skull Base Surgery

Director, Skull Base Tumor Program

Co-Director, Skull Base and Cerebrovascular Laboratory


Dr. Theodosopoulos is the Director of Skull Base Tumor Program and a Professor and Vice Chairman of neurological surgery at UCSF. Before joining the faculty at UCSF, he served as the Residency Program Director and the Director of Skull Base Surgery at the University of Cincinnati for 10 years. Dr. Theodosopoulos completed his undergraduate work at MIT and medical school at Stanford University. He completed his neurosurgical training at UCSF and a fellowship in cerebrovascular and skull base surgery at the Brigham and Women’s Hospital, Harvard University.

Dr. Theodosopoulos' primary clinical interests involve the treatment of skull base lesions, particularly acoustic neuromas and malignancies as well as minimally invasive approaches to the skull base. He served as the Co-Principal Investigator for the largest prospective multi-center trial of the surgical treatment of acoustic neuromas and currently serves on the Medical Advisory Board of the Acoustic Neuroma Association. He has extensive expertise in the endoscopic treatment of pituitary adenomas and chordomas and has been a pioneer in the development of new surgical approaches to the skull base. As the do-director of the Goodyear Microsurgical Laboratory at the University of Cincinnati he lead a prolific team focused on translational work related to the development of novel surgical corridors to the skull base among which the first description and clinical application of the endoscopic approach to the infratemporal fossa.

He has been faculty on more than 50 national and international surgical courses and serves on the Congress of Neurological Surgeons Education Committee. Dr Theodosopoulos also has extensive expertise in the field of Outcomes Research having completed the UCSF Outcome Research and Clinical Epidemiology full curriculum as a resident and having remained involved in outcomes research at the local and national level.

Education, Training, and Previous Positions

1992: BS, Massachusetts Institute of Technology
1996: MD, Stanford University School of Medicine
1998: Outcomes Research And Clinical Epidemiology (ORACLE),UCSF Department of Epidemiology and Biostatistics
1996-1997: Internship, General Surgery, UCSF
1997-2002: Residency in Neurosurgery, UCSF
2002-2003: Fellowship in Cerebrovascular and Skull Base Surgery, Brigham and Women's and Children's Hospital
2003-2013: Director, Division of Skull Base Surgery, Department of Neurosurgery, University of Cincinnati
2003-2013: Clinical Director, Goodyear Microsurgery Laboratory, Departments of Neurosurgery and ENT, University of Cincinnati
2003-2013: Director, Skull Base Surgery Fellowship, Department of Neurosurgery, University of Cincinnati
2003-2009: Assistant Professor, Department of Neurosurgery, University of Cincinnati
2008-2013: Director, Neurosurgery Residency Program, Department of Neurosurgery, University of Cincinnati
2009-2013: Associate Professor, Department of Neurosurgery, University of Cincinnati

Selected Professional Memberships and Appointments

Society of Neurological Surgeons 
Society of University Neurosurgeons
Congress of Neurological Surgeons
American Association of Neurological Surgeons
European Association of Neurosurgical Societies
International Stereotactic Radiosurgery Society
AANS/CNS Joint Section on Tumors
AANS/CNS Joint Section on Neurotrauma and Critical Care
California Association of Neurological Surgeons
North American Skull Base Society
Pituitary Network Association
Acoustic Neuroma Association

Selected Honors and Awards

2013: Visiting Lecturer, Department of Neurosurgery, Baylor School of
Medicine, Houston, TX 2010: Khatib Lecturer and Visiting Professor, Department of Neurological Surgery, University of California San Francisco, San Francisco, CA
2006: Franklin M. Rizer Lecturer, American Neuro-otology Society, Fall Scientific Meeting, Toronto, Canada
1997: Honorable mention for outstanding teaching in surgical core clerkship UCSF, Department of Surgery
1996: Dean’s award for Distinguished Research in Neurobiology, Stanford University School of Medicine
1993: Hellenic Medical and Dental Association award for excellence in the Health Sciences
1993: Medical Scholars scholarship, Stanford University School of Medicine

Selected Recent Publications

Kurbanov A, Zimmer LA, Theodosopoulos PV, Leach JL, Keller JT. An Endoscopic Roadmap of the Internal Carotid Artery. Neurosurgery. 2015 Apr 7. [Epub ahead of print]

Theodosopoulos PV, Ringer AJ. Measuring Outcomes for Neurosurgical Procedures. Neurosurg Clin N Am 2015;26(2):265-269.

Taylor CI, Kurbanov A, Zimmer LA, Keller JT, Theodosopoulos PV. Comparing operative exposures of the le fort I osteotomy and the expanded endoscopic endonasal approach to the clivus. J Neurol Surg B Skull Base 2015;76(1):29-34.

DePowell JJ, Froelich SC, Zimmer LA, Leach JL, Karkas A, Theodosopoulos PV, Keller JT. Segments of the internal carotid artery during endoscopic transnasal and open cranial approaches: can a uniform nomenclature apply to both? World Neurosurg 2014;82(6 Suppl):S66-71.

Breshears JD, Ivan ME, Cotter JA, Bollen AW, Theodosopoulos PV, Berger MS. Primary glioblastoma of the trigeminal nerve root entry zone: case report. J Neurosurg 2015;122(1):78-81.

Cebula H, Kurbanov A, Zimmer LA, Poczos P, Leach JL, De Battista JC, Froelich S, Theodosopoulos PV, Keller JT. Endoscopic, endonasal variability in the anatomy of the internal carotid artery. World Neurosurg 2014;82(6):e759-64.

Anaizi AN, Gantwerker EA, Pensak ML, Theodosopoulos PV. Facial nerve preservation surgery for koos grade 3 and 4 vestibular schwannomas. Neurosurgery 2014;75(6):671-5; discussion 676-7; quiz 677.

Zimmer LA, Shah O, Theodosopoulos PV. Short-Term Quality-of-Life Changes after Endoscopic Pituitary Surgery Rated with SNOT-22. J Neurol Surg B Skull Base 2014;75(4):288-92.

Kerr RG, Tobler WD, Leach JL, Theodosopoulos PV, Kocaeli H, Zimmer LA, Keller JT. Anatomic variation of the optic strut: classification schema, radiologic evaluation, and surgical relevance. J Neurol Surg B Skull Base 2012;73(6):424-9.

Grewal SS, Kurbanov A, Anaizi A, Keller JT, Theodosopoulos PV, Zimmer LA. Endoscopic endonasal approach to the maxillary strut: anatomical review and case series. Laryngoscope 2014;124(8):1739-43.

Son HJ, Karkas A, Buchanan P, Giurintano JP, Theodosopoulos P, Pensak ML, Samy RN. Spontaneous cerebrospinal fluid effusion of the temporal bone: repair, audiological outcomes, and obesity. Laryngoscope 2014;124(5):1204-8.

De Battista JC, Zimmer LA, Theodosopoulos PV, Froelich SC, Keller JT. Anatomy of the inferior orbital fissure: implications for endoscopic cranial base surgery. J Neurol Surg B Skull Base 2012;73(2):132-8.

Gurgel RK, Theodosopoulos PV, Jackler RK. Subtotal/near-total treatment of vestibular schwannomas. Curr Opin Otolaryngol Head Neck Surg 2012;20(5):380-4.

Sun GH, Shoman NM, Theodosopoulos PV, Kendler A, Pensak ML. Intravascular papillary endothelial hyperplasia of the internal auditory canal. Laryngoscope 2012;122(1):212-5.

Theodosopoulos PV, Ringer AJ, McPherson CM, Warnick RE, Kuntz C 4th, Zuccarello M, Tew JM Jr. Measuring surgical outcomes in neurosurgery: implementation, analysis, and auditing a prospective series of more than 5000 procedures. J Neurosurg 2012;117(5):947-54.

De Battista JC, Zimmer LA, Rodríguez-Vázquez JF, Froelich SC, Theodosopoulos PV, DePowell JJ, Keller JT. Muller's muscle, no longer vestigial in endoscopic surgery. World Neurosurg 2011;76(3-4):342-6.

Theodosopoulos PV, Pensak ML. Contemporary management of acoustic neuromas. Laryngoscope 2011;121(6):1133-7.

Guthikonda B, Tobler WD Jr, Froelich SC, Leach JL, Zimmer LA, Theodosopoulos PV, Tew JM Jr, Keller JT. Anatomic study of the prechiasmatic sulcus and its surgical implications. Clin Anat 2010;23(6):622-8.

Guthikonda B, Pensak ML, Theodosopoulos PV. Delayed facial palsy after the anterior petrosal approach: case report and review of the literature. Neurosurgery 2010;66(4):E845-6.

Hart CK, Theodosopoulos PV, Zimmer LA. Anatomy of the optic canal: a computed tomography study of endoscopic nerve decompression. Ann Otol Rhinol Laryngol 2009;118(12):839-44.

Hart CK, Theodosopoulos PV, Zimmer LA. Olfactory changes after endoscopic pituitary tumor resection. Otolaryngol Head Neck Surg 2010;142(1):95-7.

Theodosopoulos PV, Guthikonda B, Brescia A, Keller JT, Zimmer LA. Endoscopic approach to the infratemporal fossa: anatomic study. Neurosurgery 2010;66(1):196-203.

Theodosopoulos PV, Leach J, Kerr RG, Zimmer LA, Denny AM, Guthikonda B, Froelich S, Tew JM. Maximizing the extent of tumor resection during transsphenoidal surgery for pituitary macroadenomas: can endoscopy replace intraoperative magnetic resonance imaging? J Neurosurg 2010;112(4):736-43.

Burkart CM, Theodosopoulos PV, Keller JT, Zimmer LA. Endoscopic transnasal approach to the clivus: a radiographic anatomical study. Laryngoscope 2009;119(9):1672-8.

Zimmer LA, Hart C, Theodosopoulos PV. Endoscopic anatomy of the petrous segment of the internal carotid artery. Am J Rhinol Allergy 2009;23(2):192-6.

Zimmer LA, Theodosopoulos PV. Anterior skull base surgery: open versus endoscopic. Curr Opin Otolaryngol Head Neck Surg 2009;17(2):75-8.

Kerr RG, Hearst MJ, Samy RN, van Loveren HR, Tew JM Jr, Pensak ML, Theodosopoulos PV. Delayed extrusion of hydroxyapatite cement after transpetrosal reconstruction. Neurosurgery 2009;64(3):527-32.

Froelich SC, Abdel Aziz KM, Levine NB, Pensak ML, Theodosopoulos PV, Keller JT. Exposure of the distal cervical segment of the internal carotid artery using the trans-spinosum corridor: cadaveric study of surgical anatomy. Neurosurgery 2008;62(5 Suppl 2):ONS354-612.

Froelich S, Aziz KA, Levine NB, Tew JM Jr, Keller JT, Theodosopoulos PV. Extension of the one-piece orbitozygomatic frontotemporal approach to the glenoid fossa: cadaveric study. Neurosurgery 2008;62(5 Suppl 2):ONS312-7.