Michael W. McDermott MD

Michael McDermott MD

Professor in Residence of Neurological Surgery, Halperin Endowed Chair

Neurosurgical Director, UCSF Gamma Knife® Radiosurgery Program

Vice Chairman, Department of Neurological Surgery, UCSF

Dr. McDermott's clinical specialty interests include stereotactic neurosurgery and Gamma Knife® radiosurgery, in particular for tumors of the central nervous system, meningiomas, and skull base surgery. Co-director of the UCSF Gamma Knife® Radiosurgery Program, he also practices in the Department's Adult Brain Tumor Program, Clinical Neuro-Oncology Program, Central Nervous System Infections and AIDS Program, and Hydrocephalus and Shunt Program for Adults.

Dr. McDermott's research includes studies related to malignant meningiomas and novel agents for treatment, toxicity to normal tissue after radiosurgery in a rat model, and the ability of a biologic compound to enhance the delivery of oxygen to tumors and thereby increase the effectiveness of therapy. Dr. McDermott's clinical research is focused on correlations of intraoperative tumor pathology with spectroscopy of genetic markers in primary brain tumors and comparative genomic hybridization techniques, and he is a participating research clinician in the human gene therapy clinical trials at UCSF.

Education, Training, and Previous Positions

1978: BS, University of Toronto
1982: MD, University of Toronto Medical School
1982-1983: Mixed Internship, St. Michael's Hospital, Toronto, Ontario
1983-1988: Neurosurgery Residency, University of British Columbia
1988-1989: Clinical Instructor, Neuro-Oncology Service, Brain Tumor Research Center, UCSF
1989-1990: Research Fellow, UCSF
1990-1992: Assistant Clinical Professor, Division of Neurosurgery, Department of Surgery, University of British Columbia
1992-1998: Assistant Professor, Department of Neurological Surgery, UCSF
1998-2004: Associate Professor, Department of Neurological Surgery, UCSF
2004-present: Professor, Department of Neurological Surgery, UCSF

Selected Professional Memberships and Appointments

Canadian Medical Association
Fellow, Royal College of Physicians and Surgeons of Canada
Canadian Neurosurgical Society
American Association of Neurological Surgeons: Joint Section on Tumors and Joint Section on Stereotactic and Functional Neurosurgery
Foundation for International Education in Neurological Surgery
California Neurosurgical Society
North American Skull Base Society
American Society of Stereotactic and Functional Neurosurgery
International Society for Functional & Stereotactic Neurosurgery
Society for Neuro-oncology
Congress of Neurological Surgeons

Selected Honors and Awards

1982: Frank K. Horner Silver Medal Award, Graduate with Honors, University of Toronto Medical School
1988: Graduating Residents Award, Department of Surgery, University of British Columbia
1991: Master Teacher in Surgery Award, Department of Surgery, University of British Columbia
1995: Harold Rosegay Resident Teaching Award, Department of Neurological Surgery, University of California, San Francisco

Selected Recent Publications

Jahangiri A, Chin AT, Wagner JR, Kunwar S, Ames C, Chou D, Barani I, Parsa AT, McDermott MW, Benet A, El-Sayed IH, Aghi MK. Factors predicting recurrence after resection of clival chordoma using variable surgical approaches and radiation modalities. Neurosurgery 2015;76(2):179-85; discussion 185-6.

Ivan ME, Bryan Iorgulescu J, El-Sayed I, McDermott MW, Parsa AT, Pletcher SD, Jahangiri A, Wagner J, Aghi MK. Risk factors for postoperative cerebrospinal fluid leak and meningitis after expanded endoscopic endonasal surgery. J Clin Neurosci 2015;22(1):48-54.

Desai SJ, Lawton MT, McDermott MW, Horton JC. Vertical diplopia and ptosis from removal of the orbital roof in pterional craniotomy. Ophthalmology 2015;122(3):631-8.

Abla AA, Rutledge WC, Seymour ZA, Guo D, Kim H, Gupta N, Sneed PK, Barani IJ, Larson D, McDermott MW, Lawton MT. A treatment paradigm for high-grade brain arteriovenous malformations: volume-staged radiosurgical downgrading followed by microsurgical resection. J Neurosurg 2015;122(2):419-32.

Osorio JA, Benet A, Hess CP, McDermott MW, Abla AA. Primary vertebral artery reanastomosis during retrosigmoid skull base approach following iatrogenic near-transection with monopolar electrocautery. Neurosurgery 2014;10 Suppl 4:631-9.

Zygourakis CC, Sughrue ME, Benet A, Parsa AT, Berger MS, McDermott MW. Management of planum/olfactory meningiomas: predicting symptoms and postoperative complications. World Neurosurg 2014;82(6):1216-23.

Zygourakis CC, Kaur G, Kunwar S, McDermott MW, Madden M, Oh T, Parsa AT. Modern treatment of 84 newly diagnosed craniopharyngiomas. J Clin Neurosci 2014;21(9):1558-66.

Kram YA, Lustig LR, McDermott MW, Cheung SW. Transcanal blind sac closure of the external auditory canal after skull base surgery to treat CSF leak: technique and results. Otol Neurotol 2015;36(2):307-10.

Wang DD, Lau D, Rolston JD, Englot DJ, Sneed PK, McDermott MW. Pain experience using conventional versus angled anterior posts during stereotactic head frame placement for radiosurgery. J Clin Neurosci 2014;21(9):1538-42.

Potts MB, Sheth SA, Louie J, Smyth MD, Sneed PK, McDermott MW, Lawton MT, Young WL, Hetts SW, Fullerton HJ, Gupta N. Stereotactic radiosurgery at a low marginal dose for the treatment of pediatric arteriovenous malformations: obliteration, complications, and functional outcomes. J Neurosurg Pediatr 2014;14(1):1-11.

Safaee M, Oh T, Sun MZ, Parsa AT, McDermott MW, El-Sayed IH, Bloch O. Pigmented villonodular synovitis of the temporomandibular joint with intracranial extension: A case series and systematic review. Head Neck. 2014 Apr 25. doi: 10.1002/hed.23717. [Epub ahead of print] PubMed PMID: 24764167.

Yoon MK, Piluek WJ, Ruggiero JP, McDermott MW, McCulley TJ. Orbital cerebrospinal fluid accumulation after complicated pterional-orbitozygomatic craniotomy. J Neuroophthalmol 2014;34(4):346-9.

Potts MB, Jahangiri A, Jen M, Sneed PK, McDermott MW, Gupta N, Hetts SW, Young WL, Lawton MT; UCSF Brain AVM Study Project. Deep arteriovenous malformations in the basal ganglia, thalamus, and insula: multimodality management, patient selection, and results. World Neurosurg 2014;82(3-4):386-94.

Santarius T, Jian BJ, Englot D, McDermott MW. Delayed neurological deficit following resection of tuberculum sellae meningioma: report of two cases, one with permanent and one with reversible visual impairment. Acta Neurochir (Wien) 2014;156(6):1099-102.

Safaee M, Sun MZ, Oh T, Aghi MK, Berger MS, McDermott MW, Parsa AT, Bloch O. Use of thrombin-based hemostatic matrix during meningioma resection: a potential risk factor for perioperative thromboembolic events. Clin Neurol Neurosurg 2014;119:116-20.

Oh T, Safaee M, Sun MZ, Garcia RM, McDermott MW, Parsa AT, Bloch O. Surgical risk factors for post-operative pneumonia following meningioma resection. Clin Neurol Neurosurg 2014;118:76-9.

Abla AA, Lawton MT, McDermott MW. Intracranial aneurysm formation following radiation. World Neurosurg 2014;81(3-4):492-3.

Larimer P, McDermott MW, Scott BJ, Shih TT, Poisson SN. Recurrent syncope due to refractory cerebral venous sinus thrombosis and transient elevations of intracranial pressure. Neurohospitalist 2014;4(1):18-21.

Bloch O, Crane CA, Fuks Y, Kaur R, Aghi MK, Berger MS, Butowski NA, Chang SM, Clarke JL, McDermott MW, Prados MD, Sloan AE, Bruce JN, Parsa AT. Heat-shock protein peptide complex-96 vaccination for recurrent glioblastoma: a phase II, single-arm trial. Neuro Oncol 2014;16(2):274-9.

Han SJ, Saigal R, Rolston JD, Cheng JS, Lau CY, Mistry RI, McDermott MW, Berger MS. Targeted reduction in neurosurgical laboratory utilization: resident-led effort at a single academic institution. J Neurosurg 2014;120(1):173-7.

Bloch O, Safaee M, Sun MZ, Butowski NA, McDermott MW, Berger MS, Aghi MK, Parsa AT. Disseminated progression of glioblastoma after treatment with bevacizumab. Clin Neurol Neurosurg 2013;115(9):1795-801.

Rowland NC, Huang MC, Lawton MT, Carter J, Maa J, McDermott MW. Treatment of recurrent, multiloculated, obstructive hydrocephalus with suprahepatic peritoneal catheter placement. J Clin Neurosci 2013;20(7):1038-9.

Clark AJ, Jahangiri A, Garcia RM, George JR, Sughrue ME, McDermott MW, El-Sayed IH, Aghi MK. Endoscopic surgery for tuberculum sellae meningiomas: a systematic review and meta-analysis. Neurosurg Rev 2013;36(3):349-59.

Rowland NC, Jermakowicz WJ, Tihan T, El-Sayed IH, McDermott MW. Subacute cystic expansion of intracranial juvenile psammomatoid ossifying fibroma. J Neurosurg Pediatr 2013;11(6):687-91.

Safaee M, Clark AJ, Bloch O, Oh MC, Singh A, Auguste KI, Gupta N, McDermott MW, Aghi MK, Berger MS, Parsa AT. Surgical outcomes in choroid plexus papillomas: an institutional experience. J Neurooncol 2013;113(1):117-25.

Sughrue ME, Rutkowski MJ, Chen CJ, Shangari G, Kane AJ, Parsa AT, Berger MS, McDermott MW. Modern surgical outcomes following surgery for sphenoid wing meningiomas. J Neurosurg 2013;119(1):86-93. Barajas RF Jr, Hess CP, Phillips JJ, Von Morze CJ, Yu JP, Chang SM, Nelson SJ, McDermott MW, Berger MS, Cha S. Super-resolution track density imaging of glioblastoma: histopathologic correlation. AJNR Am J Neuroradiol 2013;34(7):1319-25.

Davies JM, Trinh VT, Sneed PK, McDermott MW. Radiotherapy for recurrent epidermoid cyst. J Neurooncol 2013;112(2):307-13.

Kaur G, Kane AJ, Sughrue ME, Madden M, Oh MC, Sun MZ, Safaee M, El-Sayed I, Aghi M, McDermott MW, Berger MS, Parsa AT. The prognostic implications of Hyam's subtype for patients with Kadish stage C esthesioneuroblastoma. J Clin Neurosci 2013;20(2):281-6.

Kaur G, Kane AJ, Sughrue ME, Oh M, Safaee M, Sun M, Tihan T, McDermott MW, Berger MS, Parsa AT. MIB-1 labeling index predicts recurrence in intraventricular central neurocytomas. J Clin Neurosci 2013;20(1):89-93.