Michael W. McDermott MD

Michael McDermott MD

Professor in Residence of Neurological Surgery, Halperin Endowed Chair

Neurosurgical Director, UCSF Gamma Knife® Radiosurgery Program

Vice Chairman, Department of Neurological Surgery, UCSF


Dr. Michael W. McDermott is Professor In-Residence, Vice-Chairman and Residency Program Director in the Departmemt of Neurological Surgery at UCSF Medical Center. He holds the Robert and Ruth Halperin Chair in Meningioma Research and is Co-Director of the Gamma Knife Radiosurgery Program. His clinical brain tumor interests are the surgical treatment of meningiomas and tumors of the skull base. He is a long standing member of the Brain Tumor Center at UCSF. His research interest is meningiomas and with the help of funds from the Linda Wolfe Meningioma Endowment he has worked with scientists in the Brain Tumor Center on several basic science projects.

He earned a medical degree cum laude from the University of Toronto. After completing a residency in neurosurgery at the University of British Columbia, he was awarded a research fellowship in the Neuro-Oncology Program of the Brain Tumor Research Center at UCSF Medical Center. After a two year period back in Vancouver he returned to UCSF in September 1992 and has remained at UCSF since.

Education, Training, and Previous Positions

1978: BS, University of Toronto
1982: MD, University of Toronto Medical School
1982-1983: Mixed Internship, St. Michael's Hospital, Toronto, Ontario
1983-1988: Neurosurgery Residency, University of British Columbia
1988-1989: Clinical Instructor, Neuro-Oncology Service, Brain Tumor Research Center, UCSF
1989-1990: Research Fellow, UCSF
1990-1992: Assistant Clinical Professor, Division of Neurosurgery, Department of Surgery, University of British Columbia
1992-1998: Assistant Professor, Department of Neurological Surgery, UCSF
1998-2004: Associate Professor, Department of Neurological Surgery, UCSF
2004-present: Professor, Department of Neurological Surgery, UCSF

Selected Professional Memberships and Appointments

Canadian Medical Association
Fellow, Royal College of Physicians and Surgeons of Canada
Canadian Neurosurgical Society
American Association of Neurological Surgeons: Joint Section on Tumors and Joint Section on Stereotactic and Functional Neurosurgery
Foundation for International Education in Neurological Surgery
California Neurosurgical Society
North American Skull Base Society
American Society of Stereotactic and Functional Neurosurgery
International Society for Functional & Stereotactic Neurosurgery
Society for Neuro-oncology
Congress of Neurological Surgeons

Selected Honors and Awards

1982: Frank K. Horner Silver Medal Award, Graduate with Honors, University of Toronto Medical School
1988: Graduating Residents Award, Department of Surgery, University of British Columbia
1991: Master Teacher in Surgery Award, Department of Surgery, University of British Columbia
1995: Harold Rosegay Resident Teaching Award, Department of Neurological Surgery, University of California, San Francisco

Selected Recent Publications

Magill ST, Lee DS, Yen AJ, Lucas CG, Raleigh DR, Aghi MK, Theodosopoulos PV, McDermott MW. Surgical outcomes after reoperation for recurrent skull base meningiomas. J Neurosurg. 2018 May 4:1-8. doi: 10.3171/2017.11.JNS172278. [Epub ahead of print] PubMed PMID: 29726777.

Osorio JA, Safaee MM, Viner J, Sankaran S, Imershein S, Adigun E, Weigel G, Berger MS, McDermott MW. Cost-effectiveness development for the postoperative care of craniotomy patients: a safe transitions pathway in neurological surgery. Neurosurg Focus. 2018 May;44(5):E19. doi: 10.3171/2018.2.FOCUS1812. PubMed PMID: 29712529.

Magill ST, Rick JW, Chen WC, Haase DA, Raleigh DR, Aghi MK, Theodosopoulos PV, McDermott MW. Petrous Face Meningiomas: Classification, Clinical Syndromes, and Surgical Outcomes. World Neurosurg. 2018 Apr 4. pii: S1878-8750(18)30676-4. doi: 10.1016/j.wneu.2018.03.194. [Epub ahead of print] PubMed PMID: 29626689.

Chen WC, Magill ST, Wu A, Vasudevan HN, Morin O, Aghi MK, Theodosopoulos PV, Perry A, McDermott MW, Sneed PK, Braunstein SE, Raleigh DR. Histopathological features predictive of local control of atypical meningioma after surgery and adjuvant radiotherapy. J Neurosurg. 2018 Apr 6:1-8. doi: 10.3171/2017.9.JNS171609. [Epub ahead of print] PubMed PMID: 29624151.

McDermott MW, Ohata K, Benes V. Introduction. Skull base meningioma treatment strategies. Neurosurg Focus. 2018 Apr;44(4):E1. doi: 10.3171/2018.1.FOCUS1843. PubMed PMID: 29606055.

Magill ST, Young JS, Chae R, Aghi MK, Theodosopoulos PV, McDermott MW. Relationship between tumor location, size, and WHO grade in meningioma. Neurosurg Focus. 2018 Apr;44(4):E4. doi: 10.3171/2018.1.FOCUS17752. PubMed PMID: 29606048.

Magill ST, Morshed RA, Lucas CG, Aghi MK, Theodosopoulos PV, Berger MS, de Divitiis O, Solari D, Cappabianca P, Cavallo LM, McDermott MW. Tuberculum sellae meningiomas: grading scale to assess surgical outcomes using the transcranial versus transsphenoidal approach. Neurosurg Focus. 2018 Apr;44(4):E9. doi: 10.3171/2018.1.FOCUS17753. PubMed PMID: 29606045.

Vasudevan HN, Braunstein SE, Phillips JJ, Pekmezci M, Tomlin BA, Wu A, Reis GF, Magill ST, Zhang J, Feng FY, Nicholaides T, Chang SM, Sneed PK, McDermott MW, Berger MS, Perry A, Raleigh DR. Comprehensive Molecular Profiling Identifies FOXM1 as a Key Transcription Factor for Meningioma Proliferation. Cell Rep. 2018 Mar 27;22(13):3672-3683. doi: 10.1016/j.celrep.2018.03.013. PubMed PMID: 29590631.

Breshears JD, Chang J, Molinaro AM, Sneed PK, McDermott MW, Tward A, Theodosopoulos PV. Temporal Dynamics of Pseudoprogression After Gamma Knife Radiosurgery for Vestibular Schwannomas-A Retrospective Volumetric Study. Neurosurgery. 2018 Mar 5. doi: 10.1093/neuros/nyy019. [Epub ahead of print] PubMed PMID: 29518221.

Chen WC, Hara J, Magill ST, Wu A, Aghi MK, Theodosopoulos PV, Perry A, McDermott MW, Sneed PK, Raleigh DR, Braunstein SE. Salvage therapy outcomes for atypical meningioma. J Neurooncol. 2018 Jun;138(2):425-433. doi: 10.1007/s11060-018-2813-9. Epub 2018 Feb 26. PubMed PMID: 29480505.

Flanigan PM, Jahangiri A, Weinstein D, Dayani F, Chandra A, Kanungo I, Choi S, Sankaran S, Molinaro AM, McDermott MW, Berger MS, Aghi MK. Postoperative Delirium in Glioblastoma Patients: Risk Factors and Prognostic Implications. Neurosurgery. 2018 Feb 16. doi: 10.1093/neuros/nyx606. [Epub ahead of print] PubMed PMID: 29462362.

Yu Y, El-Sayed IH, McDermott MW, Theodosopoulos PV, van Zante A, Kased N, Glastonbury CM, Garsa AA, Yom SS. Dural recurrence among esthesioneuroblastoma patients presenting with intracranial extension. Laryngoscope. 2018 Feb 10. doi: 10.1002/lary.27126. [Epub ahead of print] PubMed PMID: 29427378.

Wu A, Garcia MA, Magill ST, Chen W, Vasudevan HN, Perry A, Theodosopoulos PV, McDermott MW, Braunstein SE, Raleigh DR. Presenting Symptoms and Prognostic Factors for Symptomatic Outcomes Following Resection of Meningioma. World Neurosurg. 2018 Mar;111:e149-e159. doi: 10.1016/j.wneu.2017.12.012. Epub 2017 Dec 14. PubMed PMID: 29248774.

Sizdahkhani S, Magill ST, McDermott MW. Intraventricular Meningioma Resection with Postoperative Ischemia of the Lateral Geniculate Nucleus. World Neurosurg. 2017 Oct;106:878-883. doi: 10.1016/j.wneu.2017.07.067. Epub 2017 Jul 19. PubMed PMID: 28735134.

Vasudevan HN, Raleigh DR, Johnson J, Garsa AA, Theodosopoulos PV, Aghi MK, Ames C, McDermott MW, Barani IJ, Braunstein SE. Management of Chordoma and Chondrosarcoma with Fractionated Stereotactic Radiotherapy. Front Surg. 2017 Jun 23;4:35. doi: 10.3389/fsurg.2017.00035. eCollection 2017. PubMed PMID: 28691010; PubMed Central PMCID: PMC5481320.

Cage T, Bach A, McDermott MW. Use of Subdural Evacuating Port System Following Open Craniotomy with Excision of Native Dura and Membranes for Management of Chronic Subdural Hematoma. Cureus. 2017 Apr 26;9(4):e1197. doi: 10.7759/cureus.1197. PubMed PMID: 28560123; PubMed Central PMCID: PMC5446221.

Safaee MM, McDermott MW, Benet A, Theodosopoulos PV. Tailored Extended Bifrontal Craniotomy for Anterior Skull Base Tumors: Anatomic Description of a Modified Surgical Technique and Case Series. Oper Neurosurg (Hagerstown). 2018 Apr 1;14(4):386-394. doi: 10.1093/ons/opx134. PubMed PMID: 28541579.

Flanigan PM, Jahangiri A, Kuang R, Truong A, Choi S, Chou A, Rick JW, Chang SM, Molinaro AM, McDermott MW, Berger MS, Aghi MK. Improved Survival with Decreased Wait Time to Surgery in Glioblastoma Patients Presenting with Seizure. Neurosurgery. 2017 Nov 1;81(5):824-833. doi: 10.1093/neuros/nyx084. PubMed PMID: 28541497.

Chan AK, Birk HS, Yue JK, Winkler EA, McDermott MW. Bilateral External Ventricular Drain Placement and Intraventricular Irrigation Combined with Concomitant Serial Prone Patient Positioning: A Novel Treatment for Gravity-Dependent Layering in Bacterial Ventriculitis. Cureus. 2017 Apr 18;9(4):e1175. doi: 10.7759/cureus.1175. PubMed PMID: 28533993; PubMed Central PMCID: PMC5436887.

Flanigan PM, Jahangiri A, Kuang R, Truong A, Choi S, Chou A, Molinaro AM, McDermott MW, Berger MS, Aghi MK. Developing an Algorithm for Optimizing Care of Elderly Patients With Glioblastoma. Neurosurgery. 2018 Jan 1;82(1):64-75. doi: 10.1093/neuros/nyx148. PubMed PMID: 28475720.

Jahangiri A, Chin AT, Wagner JR, Kunwar S, Ames C, Chou D, Barani I, Parsa AT, McDermott MW, Benet A, El-Sayed IH, Aghi MK. In Reply: Factors Predicting Recurrence After Resection of Clival Chordoma Using Variable Surgical Approaches and Radiation Modalities. Neurosurgery. 2017 Aug 1;81(2):E32. doi: 10.1093/neuros/nyx137. PubMed PMID: 28379552.

Chen WC, Magill ST, Englot DJ, Baal JD, Wagle S, Rick JW, McDermott MW. Factors Associated With Pre- and Postoperative Seizures in 1033 Patients Undergoing Supratentorial Meningioma Resection. Neurosurgery. 2017 Aug 1;81(2):297-306. doi: 10.1093/neuros/nyx001. PubMed PMID: 28327947; PubMed Central PMCID: PMC5572484.

Zygourakis CC, Keefe M, Lee J, Barba J, McDermott MW, Mummaneni PV, Lawton MT. Comparison of Patient Outcomes in 3725 Overlapping vs 3633 Nonoverlapping Neurosurgical Procedures Using a Single Institution's Clinical and Administrative Database. Neurosurgery. 2017 Feb 1;80(2):257-268. doi: 10.1093/neuros/nyw067. PubMed PMID: 28173545.

Magill ST, Theodosopoulos PV, McDermott MW. Resection of falx and parasagittal meningioma: complication avoidance. J Neurooncol. 2016 Nov;130(2):253-262. Epub 2016 Oct 24. Review. PubMed PMID: 27778211.

Winkler EA, Birk H, Safaee M, Yue JK, Burke JF, Viner JA, Pekmezci M, Perry A, Aghi MK, Berger MS, McDermott MW. Surgical resection of fourth ventricular ependymomas: case series and technical nuances. J Neurooncol. 2016 Nov;130(2):341-349. Epub 2016 Oct 24. Review. Erratum in: J Neurooncol. 2017 Jan;131(2):423. PubMed PMID: 27778210.

Cohen-Gadol A, McDermott MW. Introduction: special issue on operative neurosurgical oncology. J Neurooncol. 2016 Nov;130(2):241. PubMed PMID: 27699632.

Lum MA, Martin AJ, Alexander MD, McCoy DB, Cooke DL, Lillaney P, Moftakhar P, Amans MR, Settecase F, Nicholson A, Dowd CF, Halbach VV, Higashida RT, McDermott MW, Saloner D, Hetts SW. Intra-Arterial MR Perfusion Imaging of Meningiomas: Comparison to Digital Subtraction Angiography and Intravenous MR Perfusion Imaging. PLoS One. 2016 Nov 1;11(11):e0163554. doi: 10.1371/journal.pone.0163554. eCollection 2016. PubMed PMID: 27802268; PubMed Central PMCID: PMC5089755.

Ma L, Braunstein SE, Theodosopoulos PV, McDermott MW, Sneed PK. Inherent functional dependence among cochlear dose surrogates for stereotactic radiosurgery of vestibular schwannomas. Pract Radiat Oncol. 2017 Jan - Feb;7(1):e1-e7. doi: 10.1016/j.prro.2016.08.005. Epub 2016 Aug 20. PubMed PMID: 27742557.

Chiu J, Pierce M, Braunstein SE, Theodosopoulos PV, McDermott MW, Sneed PK, Ma L. Sharpening peripheral dose gradient via beam number enhancement from patient head tilt for stereotactic brain radiosurgery. Phys Med Biol. 2016 Oct 3;61(20):N532-N541. [Epub ahead of print] PubMed PMID: 27694708.

Han SJ, Reis G, Kohanbash G, Shrivastav S, Magill ST, Molinaro AM, McDermott MW, Theodosopoulos PV, Aghi MK, Berger MS, Butowski NA, Barani I, Phillips JJ, Perry A, Okada H. Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma. J Neurooncol. 2016 Dec;130(3):543-552. Epub 2016 Sep 13. PubMed PMID: 27624915; PubMed Central PMCID: PMC5560602.

Chan AK, Birk HS, Winkler EA, Viner JA, Taylor JW, McDermott MW. Stability of Programmable Shunt Valve Settings with Simultaneous Use of the Optune Transducer Array: A Case Report. Cureus. 2016 Jul 7;8(7):e675. doi: 10.7759/cureus.675. PubMed PMID: 27551653; PubMed Central PMCID: PMC4977218.

Cage T, Benet A, Golfinos J, McDermott MW. A Superior Cerebellar Convexity Two-Part Craniotomy to Access the Paramedian Supra and Infratentorial Space: Technical Note. Cureus. 2016 Jun 30;8(6):e664. doi: 10.7759/cureus.664. PubMed PMID: 27493846; PubMed Central PMCID: PMC4968780.

Imber BS, Kanungo I, Braunstein S, Barani IJ, Fogh SE, Nakamura JL, Berger MS, Chang EF, Molinaro AM, Cabrera JR, McDermott MW, Sneed PK, Aghi MK. Indications and Efficacy of Gamma Knife Stereotactic Radiosurgery for Recurrent Glioblastoma: 2 Decades of Institutional Experience. Neurosurgery. 2017 Jan 1;80(1):129-139. doi: 10.1227/NEU.0000000000001344. PubMed PMID: 27428784; PubMed Central PMCID: PMC5235998.

Raleigh DR, Seymour ZA, Tomlin B, Theodosopoulos PV, Berger MS, Aghi MK, Geneser SE, Krishnamurthy D, Fogh SE, Sneed PK, McDermott MW. Resection and brain brachytherapy with permanent iodine-125 sources for brain metastasis. J Neurosurg. 2017 Jun;126(6):1749-1755. doi: 10.3171/2016.4.JNS152530. Epub 2016 Jul 1. PubMed PMID: 27367240.

Raleigh DR, Solomon DA, Lloyd SA, Lazar A, Garcia MA, Sneed PK, Clarke JL, McDermott MW, Berger MS, Tihan T, Haas-Kogan DA. Histopathologic review of pineal parenchymal tumors identifies novel morphologic subtypes and prognostic factors for outcome. Neuro Oncol. 2017 Jan;19(1):78-88. doi: 10.1093/neuonc/now105. Epub 2016 Jun 9. PubMed PMID: 27282397; PubMed Central PMCID: PMC5193017.

Magill ST, Lau D, Raleigh DR, Sneed PK, Fogh SE, McDermott MW. Surgical Resection and Interstitial Iodine-125 Brachytherapy for High-Grade Meningiomas: A 25-Year Series. Neurosurgery. 2017 Mar 1;80(3):409-416. doi: 10.1227/NEU.0000000000001262. PubMed PMID: 27258768.

Shah JK, Potts MB, Sneed PK, Aghi MK, McDermott MW. Surgical Cavity Constriction and Local Progression Between Resection and Adjuvant Radiosurgery for Brain Metastases. Cureus. 2016 Apr 19;8(4):e575. doi: 10.7759/cureus.575. PubMed PMID: 27226936; PubMed Central PMCID: PMC4873317.

Castro BA, Imber BS, Chen R, McDermott MW, Aghi MK. Ventriculoperitoneal Shunting for Glioblastoma: Risk Factors, Indications, and Efficacy. Neurosurgery. 2017 Mar 1;80(3):421-430. doi: 10.1227/NEU.0000000000001263. PubMed PMID: 27218235.

Safaee M, Burke J, McDermott MW. Techniques for the Application of Stereotactic Head Frames Based on a 25-Year Experience. Cureus. 2016 Mar 25;8(3):e543. doi: 10.7759/cureus.543. PubMed PMID: 27158573; PubMed Central PMCID: PMC4846396.

Kaprealian T, Raleigh DR, Sneed PK, Nabavizadeh N, Nakamura JL, McDermott MW. Parameters influencing local control of meningiomas treated with radiosurgery. J Neurooncol. 2016 Jun;128(2):357-64. doi: 10.1007/s11060-016-2121-1. Epub 2016 Apr 30. PubMed PMID: 27131883.

Birk HS, Han SJ, Rolston JD, Rowland NC, Lau C, Theodosopoulos PV, McDermott MW. Resident-led Implementation of a Standardized Handoff System to Facilitate Transfer of Postoperative Neurosurgical Patients to the ICU. Cureus. 2016 Jan 18;8(1):e461. doi: 10.7759/cureus.461. PubMed PMID: 26929888; PubMed Central PMCID: PMC4762767.

Han SJ, Rolston JD, Zygourakis CC, Sun MZ, McDermott MW, Lau CY, Aghi MK. Preventing Delays in First-Case Starts on the Neurosurgery Service: A Resident-Led Initiative at an Academic Institution. J Surg Educ. 2016 Mar-Apr;73(2):291-5. doi: 10.1016/j.jsurg.2015.09.018. Epub 2016 Jan 13. PubMed PMID: 26774935.

Han SJ, Magill ST, Tarapore PE, Horton JC, McDermott MW. Direct visualization of improved optic nerve pial vascular supply following tuberculum meningioma resection: case report. J Neurosurg. 2016 Sep;125(3):565-9. doi: 10.3171/2015.6.JNS15765. Epub 2015 Dec 18. PubMed PMID: 26684783; PubMed Central PMCID: PMC5125447.

Englot DJ, Magill ST, Han SJ, Chang EF, Berger MS, McDermott MW. Seizures in supratentorial meningioma: a systematic review and meta-analysis. J Neurosurg. 2016 Jun;124(6):1552-61. doi: 10.3171/2015.4.JNS142742. Epub 2015 Dec 4. Review. PubMed PMID: 26636386; PubMed Central PMCID: PMC4889504.

Lau D, Hervey-Jumper SL, Chang S, Molinaro AM, McDermott MW, Phillips JJ, Berger MS. A prospective Phase II clinical trial of 5-aminolevulinic acid to assess the correlation of intraoperative fluorescence intensity and degree of histologic cellularity during resection of high-grade gliomas. J Neurosurg. 2016 May;124(5):1300-9. doi: 10.3171/2015.5.JNS1577. Epub 2015 Nov 6. PubMed PMID: 26544781.

Seymour ZA, Sneed PK, Gupta N, Lawton MT, Molinaro AM, Young W, Dowd CF, Halbach VV, Higashida RT, McDermott MW. Volume-staged radiosurgery for large arteriovenous malformations: an evolving paradigm. J Neurosurg. 2016 Jan;124(1):163-74. doi: 10.3171/2014.12.JNS141308. Epub 2015 Jul 3. PubMed PMID: 26140495.

Chang JS, Ma L, Barani IJ, McDermott MW, Sneed PK, Larson DA. Hippocampal Dose With Radiosurgery for Multiple Intracranial Targets: The Rationale for Proactive Beam Shaping. Technol Cancer Res Treat. 2016 Aug;15(4):555-9. doi: 10.1177/1533034615590934. Epub 2015 Jun 25. PubMed PMID: 26113558.